1-beta-D-Arabinofuranosyl-N(sup 4)-palmitoylcytosine

Base Information

Chemical Name:1-beta-D-Arabinofuranosyl-N(sup 4)-palmitoylcytosine
CAS No.:55726-45-9
Molecular Formula:C₂₅H₄₃N₃O₆
Molecular Weight:481.633
Hs Code.:
UNII:O57A51JE0D
Nikkaji Number:J22.924E
Wikidata:Q27285356
ChEMBL ID:CHEMBL3350506
Mol file:55726-45-9.mol

Synonyms:N(4)-palmitoyl cytarabine;N(4)-palmitoyl-ara-C

Suppliers and Price of 1-beta-D-Arabinofuranosyl-N(sup 4)-palmitoylcytosine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 1-beta-D-Arabinofuranosyl-N(sup 4)-palmitoylcytosine

Chemical Property:

Refractive Index:1.7120 (estimate)
Boiling Point:°Cat760mmHg
Flash Point:°C
PSA：133.91000
Density:1.23g/cm³
LogP:3.34760
XLogP3:6
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:17
Exact Mass:481.31518610
Heavy Atom Count:34
Complexity:684

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCCCCCCCCCCCCC(=O)NC1=NC(=O)N(C=C1)C2C(C(C(O2)CO)O)O
Isomeric SMILES:CCCCCCCCCCCCCCCC(=O)NC1=NC(=O)N(C=C1)[C@H]2[C@H]([C@@H]([C@H](O2)CO)O)O
Recent ClinicalTrials:Study of Safety, Efficacy, and Pharmacokinetics of Topical ACD440 in Healthy Volunteers

Technology Process of 1-beta-D-Arabinofuranosyl-N(sup 4)-palmitoylcytosine

There total 4 articles about 1-beta-D-Arabinofuranosyl-N(sup 4)-palmitoylcytosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.3%

: 55726-45-9
N⁴-Palmitoyl-1-β-D-arabinofuranosylcytosin

Guidance literature:

Reference yield: 64.3%

: 57-10-3
1-hexadecylcarboxylic acid

: 147-94-4
arabinosyl cytosine

: 55726-45-9
N⁴-Palmitoyl-1-β-D-arabinofuranosylcytosin

Guidance literature:: 1-hexadecylcarboxylic acid; With chloroformic acid ethyl ester; triethylamine; In N,N-dimethyl-formamide; for 0.333333h; Inert atmosphere; Cooling with ice;

arabinosyl cytosine; In N,N-dimethyl-formamide; at 20 ℃; for 72h; Inert atmosphere;