2,3-Dihydro-N-(2-(4-morpholinyl)ethyl)-1,4-benzodioxin-2-carboximidamide dihydrochloride

Base Information

Chemical Name:2,3-Dihydro-N-(2-(4-morpholinyl)ethyl)-1,4-benzodioxin-2-carboximidamide dihydrochloride
CAS No.:130482-64-3
Molecular Formula:C₁₅H₂₁N₃O₃*2ClH
Molecular Weight:364.272
Hs Code.:
DSSTox Substance ID:DTXSID60926757
Mol file:130482-64-3.mol

Synonyms:130482-64-3;2,3-Dihydro-N-(2-(4-morpholinyl)ethyl)-1,4-benzodioxin-2-carboximidamide dihydrochloride;1,4-Benzodioxin-2-carboximidamide, 2,3-dihydro-N-(2-(4-morpholinyl)ethyl)-, dihydrochloride;1,4-Benzodioxin-2-carboximidamide, 2,3-dihydro-N-(2-(4-morpholinyl)eth yl)-, dihydrochloride;N'-(2-morpholin-4-ylethyl)-2,3-dihydro-1,4-benzodioxine-3-carboximidamide;dihydrochloride;C15H21N3O3.2ClH;DTXSID60926757;HOTKGTLXLVPZCO-UHFFFAOYSA-N;C15-H21-N3-O3.2Cl-H;LS-34556;1,4-Benzodioxin-2-carboximidamide,2,3-dihydro-N-(2-(4-morpholinyl)eth yl)-,dihydrochloride;N-[2-(Morpholin-4-yl)ethyl]-2,3-dihydro-1,4-benzodioxine-2-carboximidamide--hydrogen chloride (1/2)

Suppliers and Price of 2,3-Dihydro-N-(2-(4-morpholinyl)ethyl)-1,4-benzodioxin-2-carboximidamide dihydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1,4-BENZODIOXIN-2-CARBOXIMIDAMIDE, 2,3-DIHYDRO-N-(2-(4-MORPHOLINYL)ETH YL)-, DIHYDROCHLORIDE 95.00%
5MG
$ 500.49

Total 0 raw suppliers

Chemical Property of 2,3-Dihydro-N-(2-(4-morpholinyl)ethyl)-1,4-benzodioxin-2-carboximidamide dihydrochloride

Chemical Property:

Vapor Pressure:1.6E-08mmHg at 25°C
Boiling Point:456.6°Cat760mmHg
Flash Point:229.9°C
PSA：66.81000
Density:g/cm³
LogP:2.75800
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:363.1116470
Heavy Atom Count:23
Complexity:358

Purity/Quality:: 1,4-BENZODIOXIN-2-CARBOXIMIDAMIDE, 2,3-DIHYDRO-N-(2-(4-MORPHOLINYL)ETH YL)-, DIHYDROCHLORIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COCCN1CCN=C(C2COC3=CC=CC=C3O2)N.Cl.Cl

Technology Process of 2,3-Dihydro-N-(2-(4-morpholinyl)ethyl)-1,4-benzodioxin-2-carboximidamide dihydrochloride

There total 4 articles about 2,3-Dihydro-N-(2-(4-morpholinyl)ethyl)-1,4-benzodioxin-2-carboximidamide dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 2038-03-1
4-(2-AMINOETHYL)MORPHOLINE

: 85084-36-2
chlorure de dihydro-2,3 benzodioxinne-1,4 carboxamidinium-2

: 130482-64-3
N-(2-Morpholin-4-yl-ethyl)-2,3-dihydro-benzo[1,4]dioxine-2-carboxamidine; hydrochloride

Guidance literature:: In ethanol; for 1.5h; Heating;
DOI:10.1016/0223-5234(90)90002-K

Reference yield:

: 1008-92-0
2-cyano-1,4-benzodioxane

: 130482-64-3
N-(2-Morpholin-4-yl-ethyl)-2,3-dihydro-benzo[1,4]dioxine-2-carboxamidine; hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: 90 percent / methylate de sodium / 24 h / Ambient temperature

2: 97 percent / chlorure d'ammonium / ethanol / 3.5 h / Heating

3: 87 percent / ethanol / 1.5 h / Heating

With ammonium chloride; sodium methylate; In ethanol;
DOI:10.1016/0223-5234(90)90002-K

Reference yield:

: 96717-31-6
diethyl-2,3-dihydro-1,4-benzodioxine-2-carboximidate

: 130482-64-3
N-(2-Morpholin-4-yl-ethyl)-2,3-dihydro-benzo[1,4]dioxine-2-carboxamidine; hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: 97 percent / chlorure d'ammonium / ethanol / 3.5 h / Heating

2: 87 percent / ethanol / 1.5 h / Heating

With ammonium chloride; In ethanol;
DOI:10.1016/0223-5234(90)90002-K