methyl 5-[(2E)-3-(dimethylamino)prop-2-enoyl]-2-methoxybenzoate

Base Information

• Chemical Name: methyl 5-[(2E)-3-(dimethylamino)prop-2-enoyl]-2-methoxybenzoate
• CAS No.: 1201798-99-3
• Molecular Formula: C₁₄H₁₇NO₄
• Molecular Weight: 263.293
• Mol file: 1201798-99-3.mol

Synonyms:methyl 5-[(2E)-3-(dimethylamino)prop-2-enoyl]-2-methoxybenzoate

Chemical Property of methyl 5-[(2E)-3-(dimethylamino)prop-2-enoyl]-2-methoxybenzoate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of methyl 5-[(2E)-3-(dimethylamino)prop-2-enoyl]-2-methoxybenzoate

There total 1 articles about methyl 5-[(2E)-3-(dimethylamino)prop-2-enoyl]-2-methoxybenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-acetyl-2-methoxybenzoic acid methyl ester (39971-36-3) + N,N-dimethyl-formamide dimethyl acetal (4637-24-5) → methyl 5-[(2E)-3-(dimethylamino)prop-2-enoyl]-2-methoxybenzoate (1201798-99-3)

Guidance literature:

at 95 ℃; for 5.5h; Inert atmosphere;

Reference yield:

4-Amino-2,6-dihydroxypyrimidine (873-83-6) + methyl 5-[(2E)-3-(dimethylamino)prop-2-enoyl]-2-methoxybenzoate (1201798-99-3) → Methyl 5-(2,4-dioxo-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidin-7-yl)-2-methoxybenzoate (1201799-00-9)

Guidance literature:

With acetic acid; In water; dimethyl sulfoxide; at 99 ℃; for 4.5h;

upstream raw materials:

5-acetyl-2-methoxybenzoic acid methyl ester

N,N-dimethyl-formamide dimethyl acetal

Downstream raw materials:

Methyl 5-(2,4-dioxo-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidin-7-yl)-2-methoxybenzoate