N-([1,1'-biphenyl]-4-ylmethyl)-N-(3-chlorophenethyl)-2,4,6-trimethylbenzenesulfonamide

Base Information

• Chemical Name: N-([1,1'-biphenyl]-4-ylmethyl)-N-(3-chlorophenethyl)-2,4,6-trimethylbenzenesulfonamide
• CAS No.: 1613029-11-0
• Molecular Formula: C₃₀H₃₀ClNO₂S
• Molecular Weight: 504.093

Synonyms:N-([1,1'-biphenyl]-4-ylmethyl)-N-(3-chlorophenethyl)-2,4,6-trimethylbenzenesulfonamide

Chemical Property of N-([1,1'-biphenyl]-4-ylmethyl)-N-(3-chlorophenethyl)-2,4,6-trimethylbenzenesulfonamide

Chemical Property:

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Technology Process of N-([1,1'-biphenyl]-4-ylmethyl)-N-(3-chlorophenethyl)-2,4,6-trimethylbenzenesulfonamide

There total 2 articles about N-([1,1'-biphenyl]-4-ylmethyl)-N-(3-chlorophenethyl)-2,4,6-trimethylbenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

N-(3-chlorophenethyl)-N-(4-iodobenzyl)-2,4,6-trimethylbenzenesulfonamide (1613028-99-1) + phenylboronic acid (98-80-6) → N-([1,1'-biphenyl]-4-ylmethyl)-N-(3-chlorophenethyl)-2,4,6-trimethylbenzenesulfonamide (1613029-11-0)

Guidance literature:

With palladium diacetate; potassium carbonate; tris-(o-tolyl)phosphine; In 1,4-dioxane; water; at 90 ℃; Inert atmosphere;

DOI:10.1016/j.bioorg.2021.105540

Reference yield: 91.0%

→ N-([1,1'-biphenyl]-4-ylmethyl)-N-(3-chlorophenethyl)-2,4,6-trimethylbenzenesulfonamide (1613029-11-0)

Guidance literature:

With palladium diacetate; tris-(o-tolyl)phosphine; In 1,4-dioxane; at 90 ℃; Inert atmosphere;

upstream raw materials:

N-(3-chlorophenethyl)-N-(4-iodobenzyl)-2,4,6-trimethylbenzenesulfonamide

phenylboronic acid

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