1-(3,4-dichlorophenyl)-7-hydroxy-6-phenyl-2,3-dihydroimidazo[1,2-a]pyrimidine-5(1H)-one

Base Information

Chemical Name:1-(3,4-dichlorophenyl)-7-hydroxy-6-phenyl-2,3-dihydroimidazo[1,2-a]pyrimidine-5(1H)-one
CAS No.:1621089-24-4
Molecular Formula:C₁₈H₁₃Cl₂N₃O₂
Molecular Weight:374.226
Hs Code.:

Synonyms:1-(3,4-dichlorophenyl)-7-hydroxy-6-phenyl-2,3-dihydroimidazo[1,2-a]pyrimidine-5(1H)-one

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Chemical Property of 1-(3,4-dichlorophenyl)-7-hydroxy-6-phenyl-2,3-dihydroimidazo[1,2-a]pyrimidine-5(1H)-one

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Technology Process of 1-(3,4-dichlorophenyl)-7-hydroxy-6-phenyl-2,3-dihydroimidazo[1,2-a]pyrimidine-5(1H)-one

There total 2 articles about 1-(3,4-dichlorophenyl)-7-hydroxy-6-phenyl-2,3-dihydroimidazo[1,2-a]pyrimidine-5(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

: 83-13-6
diethyl 2-phenylmalonate

: 1-(3,4-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine hydrobromide salt

: 1621089-24-4
1-(3,4-dichlorophenyl)-7-hydroxy-6-phenyl-2,3-dihydroimidazo[1,2-a]pyrimidine-5(1H)-one

Guidance literature:: With methanol; sodium methylate; for 8h; Heating;
DOI:10.2174/1573406409666131128145844

Reference yield:

: 86109-32-2
ethyl 2-acetoxy-2-phenylacetate

: (x)BrH*C₉H₉Cl₂N₃

: 1621089-24-4
1-(3,4-dichlorophenyl)-7-hydroxy-6-phenyl-2,3-dihydroimidazo[1,2-a]pyrimidine-5(1H)-one

Guidance literature:: ethyl 2-acetoxy-2-phenylacetate; (x)BrH*C₉H₉Cl₂N₃; With sodium methylate; In methanol; for 3h; Reflux;

With hydrogenchloride; In water;
DOI:10.1016/j.molstruc.2015.04.005