[3-Hydroxy-5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)oxolan-2-yl]methyl carbamate

Base Information

Chemical Name:[3-Hydroxy-5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)oxolan-2-yl]methyl carbamate
CAS No.:5856-57-5
Molecular Formula:C₁₁H₁₅N₃O₆
Molecular Weight:285.257
Hs Code.:
NSC Number:91408
DSSTox Substance ID:DTXSID80293670
ChEMBL ID:CHEMBL2001522

Synonyms:NSC91408;5856-57-5;NSC-91408;CHEMBL2001522;DTXSID80293670;NCI60_042023;[3-hydroxy-5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)oxolan-2-yl]methyl carbamate

Suppliers and Price of [3-Hydroxy-5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)oxolan-2-yl]methyl carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 5 raw suppliers

Chemical Property of [3-Hydroxy-5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)oxolan-2-yl]methyl carbamate

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
Density:1.478g/cm³
XLogP3:-1.7
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:285.09608521
Heavy Atom Count:20
Complexity:477

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CN(C(=O)NC1=O)C2CC(C(O2)COC(=O)N)O

Technology Process of [3-Hydroxy-5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)oxolan-2-yl]methyl carbamate

There total 2 articles about [3-Hydroxy-5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)oxolan-2-yl]methyl carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 146457-45-6
Carbonic acid (2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester vinyl ester

: 5856-57-5
5-O-Carbamoyl-thymidin

Guidance literature:: With ammonia; In tetrahydrofuran; at 60 ℃; Yield given;
DOI:10.1016/S0040-4039(00)73746-4

Reference yield:

: 50-89-5,28854-96-8,3545-96-8,50-88-4
thymidine

: 5856-57-5
5-O-Carbamoyl-thymidin

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / CA lipase / tetrahydrofuran / 30 °C

2: NH₃ / tetrahydrofuran / 60 °C

With CA lipase; ammonia; In tetrahydrofuran;
DOI:10.1016/S0040-4039(00)73746-4