dimethyl-(4-o-tolyl-1-triisopropylsilanyl-1H-indol-3-ylmethyl)-amine

Base Information

• Chemical Name: dimethyl-(4-o-tolyl-1-triisopropylsilanyl-1H-indol-3-ylmethyl)-amine
• CAS No.: 406170-14-7
• Molecular Formula: C₂₇H₄₀N₂Si
• Molecular Weight: 420.714
• Mol file: 406170-14-7.mol

Synonyms:dimethyl-(4-o-tolyl-1-triisopropylsilanyl-1H-indol-3-ylmethyl)-amine

Chemical Property of dimethyl-(4-o-tolyl-1-triisopropylsilanyl-1H-indol-3-ylmethyl)-amine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of dimethyl-(4-o-tolyl-1-triisopropylsilanyl-1H-indol-3-ylmethyl)-amine

There total 1 articles about dimethyl-(4-o-tolyl-1-triisopropylsilanyl-1H-indol-3-ylmethyl)-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 22.0%

ortho-methylphenyl iodide (615-37-2) + 1-(N-triisopropylsilyl-1H-indol-3-yl)-N,N-dimethylmethanamine (146886-51-3) → dimethyl-(4-o-tolyl-1-triisopropylsilanyl-1H-indol-3-ylmethyl)-amine (406170-14-7)

Guidance literature:

1-(N-triisopropylsilyl-1H-indol-3-yl)-N,N-dimethylmethanamine; With tert.-butyl lithium; In diethyl ether; at 0 ℃; for 1h;

With zinc(II) chloride; zinc dibromide;

ortho-methylphenyl iodide; With tetrakis(triphenylphosphine) palladium⁽⁰⁾; Further stages.;

DOI:10.1021/ol017310m

Reference yield: 81.0%

dimethyl-(4-o-tolyl-1-triisopropylsilanyl-1H-indol-3-ylmethyl)-amine (406170-14-7) → 3-bromo-4-o-tolyl-1-triisopropylsilanyl-1H-indole

Guidance literature:

With N-Bromosuccinimide; In methanol; dichloromethane; at 20 ℃; for 0.0333333h;

DOI:10.1021/ol017310m

Reference yield:

dimethyl-(4-o-tolyl-1-triisopropylsilanyl-1H-indol-3-ylmethyl)-amine (406170-14-7) → dimethyl-(4-o-tolyl-1H-indol-3-ylmethyl)-amine

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃; for 0.166667h;

DOI:10.1021/ol017310m

upstream raw materials:

ortho-methylphenyl iodide

1-(N-triisopropylsilyl-1H-indol-3-yl)-N,N-dimethylmethanamine