(+)-N-[(1R,2R)-2-aminocyclohexyl]-N'-[3,5-bis(trifluoromethyl)phenyl]sulfuric diamide

Base Information

Chemical Name:(+)-N-[(1R,2R)-2-aminocyclohexyl]-N'-[3,5-bis(trifluoromethyl)phenyl]sulfuric diamide
CAS No.:1370019-23-0
Molecular Formula:C₁₄H₁₇F₆N₃O₂S
Molecular Weight:405.364
Hs Code.:

Synonyms:(+)-N-[(1R,2R)-2-aminocyclohexyl]-N'-[3,5-bis(trifluoromethyl)phenyl]sulfuric diamide

Suppliers and Price of (+)-N-[(1R,2R)-2-aminocyclohexyl]-N'-[3,5-bis(trifluoromethyl)phenyl]sulfuric diamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (+)-N-[(1R,2R)-2-aminocyclohexyl]-N'-[3,5-bis(trifluoromethyl)phenyl]sulfuric diamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (+)-N-[(1R,2R)-2-aminocyclohexyl]-N'-[3,5-bis(trifluoromethyl)phenyl]sulfuric diamide

There total 2 articles about (+)-N-[(1R,2R)-2-aminocyclohexyl]-N'-[3,5-bis(trifluoromethyl)phenyl]sulfuric diamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1370019-77-4
(3,5-bis(trifluoromethyl)phenyl)sulfamoyl chloride

: 20439-47-8
(1R,2R)-1,2-diaminocyclohexane

: 1370019-23-0
(+)-N-[(1R,2R)-2-aminocyclohexyl]-N'-[3,5-bis(trifluoromethyl)phenyl]sulfuric diamide

Guidance literature:: In dichloromethane; at 0 ℃; for 1.33333h;
DOI:10.1016/j.tetlet.2012.01.072

Reference yield:

: 328-74-5
3,5-Bis-(trifluoromethyl)aniline

: 1370019-23-0
(+)-N-[(1R,2R)-2-aminocyclohexyl]-N'-[3,5-bis(trifluoromethyl)phenyl]sulfuric diamide

Guidance literature:: Multi-step reaction with 3 steps

1: chlorosulfonic acid / dichloromethane / 0.25 h / 0 °C

2: phosphorus pentachloride / toluene / 100 °C

3: dichloromethane / 1.33 h / 0 °C

With chlorosulfonic acid; phosphorus pentachloride; In dichloromethane; toluene;
DOI:10.1016/j.tetlet.2012.01.072