5-FLUORO-2-PHENYLBENZO[D]THIAZOLE

Base Information

• Chemical Name: 5-FLUORO-2-PHENYLBENZO[D]THIAZOLE
• CAS No.: 1629-93-2
• Molecular Formula: C13H8 F N S
• Molecular Weight: 229.278
• Hs Code.: 2934999090
• Mol file: 1629-93-2.mol

Synonyms:NSC 403408

Chemical Property of 5-FLUORO-2-PHENYLBENZO[D]THIAZOLE

Chemical Property:

• Vapor Pressure: 4.46E-05mmHg at 25°C
• Boiling Point: 360.9°Cat760mmHg
• Flash Point: 172.1°C
• PSA: 41.13000
• Density: 1.304g/cm³
• LogP: 4.10240

Purity/Quality:

5-FLUORO-2-PHENYLBENZO[D]THIAZOLE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-FLUORO-2-PHENYLBENZO[D]THIAZOLE

There total 25 articles about 5-FLUORO-2-PHENYLBENZO[D]THIAZOLE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

N-(2-bromo-5-fluorophenyl)benzothioamide (1629-04-5) → 5-fluoro-2-phenyl-1,3-benzothiazole (1629-93-2)

Guidance literature:

With sodium phosphate; In dimethyl sulfoxide; at 20 ℃; for 5h; Inert atmosphere; Irradiation;

DOI:10.1021/acs.orglett.1c00235

Reference yield: 92.0%

phenylacetic acid (103-82-2) + 5-fluoro-2-iodoaniline (255724-71-1) → 5-fluoro-2-phenyl-1,3-benzothiazole (1629-93-2)

Guidance literature:

With copper(II) acetate monohydrate; sulfur; sodium hydroxide; In dimethyl sulfoxide; at 130 ℃; for 24h; Sealed tube; Inert atmosphere;

DOI:10.1055/s-0036-1589112

Reference yield: 91.0%

benzyl chloride (100-44-7) + 5-fluoro-2-iodoaniline (255724-71-1) → 5-fluoro-2-phenyl-1,3-benzothiazole (1629-93-2)

Guidance literature:

With copper(II) acetate monohydrate; sodium carbonate; sulfur; In dimethyl sulfoxide; at 130 ℃; for 24h; Schlenk technique; Inert atmosphere;

DOI:10.1016/j.tetlet.2017.05.004

upstream raw materials:

N-(2-bromo-5-fluorophenyl)benzothioamide

N-(3-fluoro-phenyl)-thiobenzamide

2-iodo-N-(phenylmethylene)-benzenamine

benzaldehyde