2-Phenylamino-ethanesulfonyl chloride; hydrochloride

Base Information

• Chemical Name: 2-Phenylamino-ethanesulfonyl chloride; hydrochloride
• CAS No.: 103020-63-9
• Molecular Formula: C₈H₁₀ClNO₂S*ClH
• Molecular Weight: 256.153
• Mol file: 103020-63-9.mol

Synonyms:2-Phenylamino-ethanesulfonyl chloride; hydrochloride

Chemical Property of 2-Phenylamino-ethanesulfonyl chloride; hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Phenylamino-ethanesulfonyl chloride; hydrochloride

There total 2 articles about 2-Phenylamino-ethanesulfonyl chloride; hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

2-anilino-ethanesulfonic acid (58928-14-6) → 2-Phenylamino-ethanesulfonyl chloride; hydrochloride (103020-63-9)

Guidance literature:

With phosphorus pentachloride; trichlorophosphate; at 90 ℃;

Reference yield:

aniline (62-53-3) → 2-Phenylamino-ethanesulfonyl chloride; hydrochloride (103020-63-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 1) MeOH, 0 deg C; 2) 10 deg C; 70 deg C, 18 h

2: 45 percent / PCl₅, POCl₃ / 90 °C

With phosphorus pentachloride; trichlorophosphate;

Reference yield: 50.0%

2-Phenylamino-ethanesulfonyl chloride; hydrochloride (103020-63-9) → 2-phenyl-1,2-thiazetidine 1,1-dioxide (85582-51-0)

Guidance literature:

With sodium carbonate; In ethyl acetate; at 110 ℃; for 48h;

upstream raw materials:

2-anilino-ethanesulfonic acid

aniline

Downstream raw materials:

2-phenyl-1,2-thiazetidine 1,1-dioxide