(S)-2-benzoyloxymethyl-2-formyl oxirane

Base Information

• Chemical Name: (S)-2-benzoyloxymethyl-2-formyl oxirane
• CAS No.: 174002-48-3
• Molecular Formula: C₁₁H₁₀O₄
• Molecular Weight: 206.198
• Mol file: 174002-48-3.mol

Synonyms:(S)-2-benzoyloxymethyl-2-formyl oxirane

Chemical Property of (S)-2-benzoyloxymethyl-2-formyl oxirane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of (S)-2-benzoyloxymethyl-2-formyl oxirane

There total 2 articles about (S)-2-benzoyloxymethyl-2-formyl oxirane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Benzoic acid (S)-2-[p-tolylsulfanyl-(2,2,2-trifluoro-acetoxy)-methyl]-oxiranylmethyl ester → (S)-2-benzoyloxymethyl-2-formyl oxirane (174002-48-3)

Guidance literature:

With potassium carbonate; mercury dichloride; In acetonitrile; Yield given; Ambient temperature;

DOI:10.1016/0957-4166(95)00359-W

Reference yield:

(2S,RS)-2-benzyloxymethyl-2-<<4-(methylphenyl)sulfinyl>methyl>oxirane (174002-46-1) → (S)-2-benzoyloxymethyl-2-formyl oxirane (174002-48-3)

Guidance literature:

Multi-step reaction with 2 steps

1: sym-collidine / acetonitrile / 0 °C

2: K₂CO₃, HgCl₂ / acetonitrile / Ambient temperature

With 2,4,6-trimethyl-pyridine; potassium carbonate; mercury dichloride; In acetonitrile;

DOI:10.1016/0957-4166(95)00359-W

Reference yield: 85.0%

(S)-2-benzoyloxymethyl-2-formyl oxirane (174002-48-3) → (S)-2-benzoyloxy-2-hydroxymethyl oxirane (174002-50-7)

Guidance literature:

With sodium tetrahydroborate; In water; acetonitrile; for 0.166667h;

DOI:10.1016/0957-4166(95)00359-W

upstream raw materials:

(2S,R_S)-2-benzyloxymethyl-2-<<4-(methylphenyl)sulfinyl>methyl>oxirane

Downstream raw materials:

(S)-2-benzoyloxy-2-hydroxymethyl oxirane