1-(2',3',4',6'-tetra-O-acetyl-β-D-galactopyranosyl)-5-cyano-6-phenyl-2-thiouracil

Base Information

• Chemical Name: 1-(2',3',4',6'-tetra-O-acetyl-β-D-galactopyranosyl)-5-cyano-6-phenyl-2-thiouracil
• CAS No.: 289906-59-8
• Molecular Formula: C₂₅H₂₅N₃O₁₀S
• Molecular Weight: 559.554

Synonyms:1-(2',3',4',6'-tetra-O-acetyl-β-D-galactopyranosyl)-5-cyano-6-phenyl-2-thiouracil

Chemical Property of 1-(2',3',4',6'-tetra-O-acetyl-β-D-galactopyranosyl)-5-cyano-6-phenyl-2-thiouracil

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(2',3',4',6'-tetra-O-acetyl-β-D-galactopyranosyl)-5-cyano-6-phenyl-2-thiouracil

There total 4 articles about 1-(2',3',4',6'-tetra-O-acetyl-β-D-galactopyranosyl)-5-cyano-6-phenyl-2-thiouracil which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

4-phenyl-6-trimethylsilanyloxy-2-trimethylsilanylsulfanyl-pyrimidine-5-carbonitrile + 1-bromo-1-deoxy-2,3,4,6-tetra-O-acetyl-a-D-galactopyranoside (3068-32-4) → 1-(2',3',4',6'-tetra-O-acetyl-β-D-galactopyranosyl)-5-cyano-6-phenyl-2-thiouracil (289906-59-8)

Guidance literature:

With tin(IV) chloride; In acetonitrile; at 23 ℃; for 16h;

DOI:10.1016/S0040-4020(00)00807-3

Reference yield: 35.0%

5-cyano-6-phenyl-2-thiouracil (70638-52-7) + 1-bromo-1-deoxy-2,3,4,6-tetra-O-acetyl-a-D-galactopyranoside (3068-32-4) → 1-(2',3',4',6'-tetra-O-acetyl-β-D-galactopyranosyl)-5-cyano-6-phenyl-2-thiouracil (289906-59-8) + Acetic acid (2R,3R,4S,5S,6R)-4,5-diacetoxy-6-acetoxymethyl-2-[5-cyano-4-oxo-6-phenyl-2-((2S,3R,4S,5S,6R)-3,4,5-triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-ylsulfanyl)-4H-pyrimidin-1-yl]-tetrahydro-pyran-3-yl ester

Guidance literature:

With potassium hydroxide; In water; acetone; at 25 ℃; for 4h;

DOI:10.1016/S0040-4039(00)00712-7

Reference yield: 35.0%

2-mercapto-6-oxo-4-phenyl-1,6-dihydro-pyrimidine-5-carbonitrile; compound with piperidine + 1-bromo-1-deoxy-2,3,4,6-tetra-O-acetyl-a-D-galactopyranoside (3068-32-4) → 1-(2',3',4',6'-tetra-O-acetyl-β-D-galactopyranosyl)-5-cyano-6-phenyl-2-thiouracil (289906-59-8) + 1-(2',3',4',6'-tetra-O-acetyl-β-D-galactopyranosyl)-2-(2'',3'',4'',6''-tetra-O-acetyl-β-D-glucopyranosylthio)-5-cyano-6-phenyl-pyrimidin-4(1H)-one

Guidance literature:

In water; acetone; at 23 ℃; for 6h;

DOI:10.1016/S0040-4020(00)00807-3

upstream raw materials:

5-cyano-6-phenyl-2-thiouracil

1-bromo-1-deoxy-2,3,4,6-tetra-O-acetyl-a-D-galactopyranoside

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 289906-59-8 1-(2',3',4',6'-tetra-O-acetyl-β-D-galactopyranosyl)-5-cyano-6-phenyl-2-thiouracil

Send

Send

Metric Ton KG G Pound L ML

Send

Send