4-methylcyclophosphamide

Base Information

• Chemical Name: 4-methylcyclophosphamide
• CAS No.: 52663-82-8
• Molecular Formula: C₈H₁₇Cl₂N₂O₂P
• Molecular Weight: 275.115
• Hs Code.: 2934999090
• Mol file: 52663-82-8.mol

Synonyms:2H-1,3,2-Oxazaphosphorine,2-[bis(2-chloroethyl)amino]tetrahydro-4-methyl-, 2-oxide (6CI);4-Methylcyclophosphamide

Chemical Property of 4-methylcyclophosphamide

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 343.2°Cat760mmHg
• Flash Point: 161.3°C
• PSA: 51.38000
• Density: 1.29g/cm³
• LogP: 2.60130

Purity/Quality:

99% ^*data from raw suppliers

4-METHYLCYCLOPHOSPHAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-methylcyclophosphamide

There total 3 articles about 4-methylcyclophosphamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ bis-(2-chloro-ethyl)-(4-methyl-2-oxo-2λ5-[1,3,2]oxazaphosphinan-2-yl)-amine (52663-82-8,57604-36-1,57604-37-2,61520-80-7,61520-81-8,61520-82-9,61520-83-0,64200-41-5,64200-42-6)

Guidance literature:

3(R)-Aminobutan-1-ol(7), N,N-Bis-(2-Chlorethyl)phosphoramiddichlorid,(C2H5)3N;

DOI:10.1021/jo00429a039

Reference yield:

→ bis-(2-chloro-ethyl)-(4-methyl-2-oxo-2λ5-[1,3,2]oxazaphosphinan-2-yl)-amine (52663-82-8,57604-36-1,57604-37-2,61520-80-7,61520-81-8,61520-82-9,61520-83-0,64200-41-5,64200-42-6)

Guidance literature:

3(R)-Aminobutan-1-ol(7), N,N-Bis-(2-Chlorethyl)phosphoramiddichlorid, Triaethylamin;

DOI:10.1021/jo00429a039

Reference yield:

→ bis-(2-chloro-ethyl)-(4-methyl-2-oxo-2λ5-[1,3,2]oxazaphosphinan-2-yl)-amine (52663-82-8)

Guidance literature:

Phosphorsaeure--dichlorid, 4-Amino-butanol-(2) in Dioxan (Triethylamin);