4-butyl-2-phenyylquinoline

Base Information

• Chemical Name: 4-butyl-2-phenyylquinoline
• CAS No.: 144757-83-5
• Molecular Formula: C₁₉H₁₉N
• Molecular Weight: 261.367
• Mol file: 144757-83-5.mol

Synonyms:4-butyl-2-phenyylquinoline

Chemical Property of 4-butyl-2-phenyylquinoline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-butyl-2-phenyylquinoline

There total 7 articles about 4-butyl-2-phenyylquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

1-phenyl-hept-2-yn-1-one (18998-78-2) + 2-iodophenylamine (615-43-0) → 4-butyl-2-phenyylquinoline (144757-83-5)

Guidance literature:

With zinc; dibromo[1,2-bis(diphenylphosphino)ethane]nickel(II); In acetonitrile; at 80 ℃; for 12h;

DOI:10.1021/jo060800d

Reference yield: 84.0%

hex-1-yne (693-02-7) + (E)-N-benzylidenebenzenamine (1750-36-3,33993-35-0,538-51-2,137431-97-1,137432-04-3) → 4-butyl-2-phenyylquinoline (144757-83-5)

Guidance literature:

With silver trifluoromethanesulfonate; copper(l) chloride; In 1,2-dichloro-ethane; at 100 ℃; for 24h;

DOI:10.1246/cl.2007.1422

Reference yield: 84.0%

Benzophenone oxime (574-66-3) + hex-1-yne (693-02-7) → 4-butyl-2-phenyylquinoline (144757-83-5)

Guidance literature:

With trifluoromethylsulfonic anhydride; In 1,2-dichloro-ethane; at 0 - 80 ℃; for 12h; regioselective reaction;

DOI:10.1002/adsc.201801724

upstream raw materials:

N-Phenylbenzonitrilium hexachloroantimonate

hex-1-yne

1-phenyl-hept-2-yn-1-one

2-iodophenylamine