Technology Process of 2-(4-(6,7-dimethoxy-4-oxo-3,4-dihydroquinazolin-2-yl)-2,6-dimethylphenoxy)acetamide
There total 3 articles about 2-(4-(6,7-dimethoxy-4-oxo-3,4-dihydroquinazolin-2-yl)-2,6-dimethylphenoxy)acetamide which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
toluene-4-sulfonic acid; sodium hydrogensulfite;
In
N,N-dimethyl acetamide;
at 150 ℃;
for 16h;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: palladium on activated charcoal; hydrogen / methanol / 20 h / 2585.81 Torr
2: sodium hydrogensulfite; toluene-4-sulfonic acid / N,N-dimethyl-formamide / 16 h / 150 °C / Inert atmosphere
With
palladium on activated charcoal; hydrogen; toluene-4-sulfonic acid; sodium hydrogensulfite;
In
methanol; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.5 h / Inert atmosphere
1.2: 36 h / 20 °C
2.1: sodium hydrogensulfite; toluene-4-sulfonic acid / N,N-dimethyl-formamide / 16 h / 150 °C / Inert atmosphere
With
sodium hydride; toluene-4-sulfonic acid; sodium hydrogensulfite;
In
N,N-dimethyl-formamide; mineral oil;
