Technology Process of 14,15,16-trinor-labd-8(20)-en-13-ol
There total 2 articles about 14,15,16-trinor-labd-8(20)-en-13-ol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
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Multi-step reaction with 5 steps
1: VO(acac)2, t-BuOOH / diethyl ether / Heating
2: LiAlH4 / diethyl ether / Heating
3: Pb(OAc)4 / benzene / Ambient temperature
4: Br2, NaOH / dioxane / Ambient temperature
5: LiAlH4 / diethyl ether / Heating
With
lead(IV) acetate; tert.-butylhydroperoxide; sodium hydroxide; lithium aluminium tetrahydride; bis(acetylacetonate)oxovanadium; bromine;
In
1,4-dioxane; diethyl ether; benzene;
DOI:10.1016/S0040-4039(97)01004-6
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 5 g / t-butyl hydroperoxide, vanadyl acetylacetonate / benzene
2: 4.7 g / LiAlH4 / diethyl ether / 1 h / Heating
3: 3.5 g / sodium periodate / H2O; methanol / Ambient temperature
4: 3.2 g / sodium hypobromite / dioxane
5: 3 g / LiAlH4
With
tert.-butylhydroperoxide; sodium periodate; lithium aluminium tetrahydride; sodium hypobromide; vanadyl acetylacetonate;
In
1,4-dioxane; methanol; diethyl ether; water; benzene;
DOI:10.1071/CH9880711
- Guidance literature:
-
Multi-step reaction with 3 steps
1: Py
2: LiBr
3: (i) MeMgI, (ii) /BRN= 7903/
With
pyridine; lithium bromide;
DOI:10.1021/ja00907a016
