N-((S)-1-hydroxy-3-methylbutan-2-yl)-4-methyl-N-((S)-3-methyl-2-(2-(4-methylphenylsulfonamido)phenylamino)butyl)benzenesulfonamide

Base Information

Chemical Name:N-((S)-1-hydroxy-3-methylbutan-2-yl)-4-methyl-N-((S)-3-methyl-2-(2-(4-methylphenylsulfonamido)phenylamino)butyl)benzenesulfonamide
CAS No.:1360632-12-7
Molecular Formula:C₃₀H₄₁N₃O₅S₂
Molecular Weight:587.805
Hs Code.:

Synonyms:N-((S)-1-hydroxy-3-methylbutan-2-yl)-4-methyl-N-((S)-3-methyl-2-(2-(4-methylphenylsulfonamido)phenylamino)butyl)benzenesulfonamide

Suppliers and Price of N-((S)-1-hydroxy-3-methylbutan-2-yl)-4-methyl-N-((S)-3-methyl-2-(2-(4-methylphenylsulfonamido)phenylamino)butyl)benzenesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of N-((S)-1-hydroxy-3-methylbutan-2-yl)-4-methyl-N-((S)-3-methyl-2-(2-(4-methylphenylsulfonamido)phenylamino)butyl)benzenesulfonamide

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-((S)-1-hydroxy-3-methylbutan-2-yl)-4-methyl-N-((S)-3-methyl-2-(2-(4-methylphenylsulfonamido)phenylamino)butyl)benzenesulfonamide

There total 7 articles about N-((S)-1-hydroxy-3-methylbutan-2-yl)-4-methyl-N-((S)-3-methyl-2-(2-(4-methylphenylsulfonamido)phenylamino)butyl)benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

: 1360632-06-9
C₃₁H₄₁N₃O₆S₂

: 1360632-12-7
N-((S)-1-hydroxy-3-methylbutan-2-yl)-4-methyl-N-((S)-3-methyl-2-(2-(4-methylphenylsulfonamido)phenylamino)butyl)benzenesulfonamide

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; at 20 ℃; for 0.5h;
DOI:10.1039/c1ob06304a

Reference yield:

: 4-methyl-2-[(2-nitrophenyl)amino]pentanoic acid

: 1360632-12-7
N-((S)-1-hydroxy-3-methylbutan-2-yl)-4-methyl-N-((S)-3-methyl-2-(2-(4-methylphenylsulfonamido)phenylamino)butyl)benzenesulfonamide

Guidance literature:: Multi-step reaction with 6 steps

1: thionyl chloride / 0 °C

2: lithium aluminium tetrahydride / tetrahydrofuran / 0.08 h / 0 - 20 °C

3: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran / 1 h / 0 °C / Inert atmosphere

4: palladium 10% on activated carbon; hydrogen / methanol / 1 h / 2585.81 Torr / Inert atmosphere

5: pyridine / 12 h / 0 °C

6: lithium aluminium tetrahydride / tetrahydrofuran / 0.5 h / 20 °C

With pyridine; lithium aluminium tetrahydride; thionyl chloride; palladium 10% on activated carbon; hydrogen; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; methanol; 3: Mitsunobu reaction;
DOI:10.1039/c1ob06304a

Reference yield:

: 1313392-70-9
(2S)-4-methyl-2-(2-nitrophenylamino)pentanoic acid methyl ester

: 1360632-12-7
N-((S)-1-hydroxy-3-methylbutan-2-yl)-4-methyl-N-((S)-3-methyl-2-(2-(4-methylphenylsulfonamido)phenylamino)butyl)benzenesulfonamide

Guidance literature:: Multi-step reaction with 5 steps

1: lithium aluminium tetrahydride / tetrahydrofuran / 0.08 h / 0 - 20 °C

2: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran / 1 h / 0 °C / Inert atmosphere

3: palladium 10% on activated carbon; hydrogen / methanol / 1 h / 2585.81 Torr / Inert atmosphere

4: pyridine / 12 h / 0 °C

5: lithium aluminium tetrahydride / tetrahydrofuran / 0.5 h / 20 °C

With pyridine; lithium aluminium tetrahydride; palladium 10% on activated carbon; hydrogen; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; methanol; 2: Mitsunobu reaction;
DOI:10.1039/c1ob06304a