N-[4-(4-hydroxy-3-isopropylphenoxy)-2,3,5-trimethylphenyl]malonamic acid

Base Information

Chemical Name:N-[4-(4-hydroxy-3-isopropylphenoxy)-2,3,5-trimethylphenyl]malonamic acid
CAS No.:373641-61-3
Molecular Formula:C₂₁H₂₅NO₅
Molecular Weight:371.433
Hs Code.:

Synonyms:N-[4-(4-hydroxy-3-isopropylphenoxy)-2,3,5-trimethylphenyl]malonamic acid

Suppliers and Price of N-[4-(4-hydroxy-3-isopropylphenoxy)-2,3,5-trimethylphenyl]malonamic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-[4-(4-hydroxy-3-isopropylphenoxy)-2,3,5-trimethylphenyl]malonamic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-[4-(4-hydroxy-3-isopropylphenoxy)-2,3,5-trimethylphenyl]malonamic acid

There total 7 articles about N-[4-(4-hydroxy-3-isopropylphenoxy)-2,3,5-trimethylphenyl]malonamic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 373641-42-0
ethyl N-[4-(4-hydroxy-3-isopropylphenoxy)-2,3,5-trimethylphenyl]malonamate

: 373641-61-3
N-[4-(4-hydroxy-3-isopropylphenoxy)-2,3,5-trimethylphenyl]malonamic acid

Guidance literature:: ethyl N-[4-(4-hydroxy-3-isopropylphenoxy)-2,3,5-trimethylphenyl]malonamate; With sodium hydroxide; In methanol; water; at 50 ℃; for 0.5h;

With hydrogenchloride; sodium chloride; In methanol; water;
DOI:10.1016/j.bmc.2012.03.056

Reference yield:

: bis(4-benzyloxy-3-isopropylphenyl)iodonium tetrafluoroborate

: 373641-61-3
N-[4-(4-hydroxy-3-isopropylphenoxy)-2,3,5-trimethylphenyl]malonamic acid

Guidance literature:: Multi-step reaction with 4 steps

1: bronze powder; triethylamine / dichloromethane / 120 h / 20 °C

2: palladium 10% on activated carbon; hydrogen / water; ethyl acetate / 20 °C

3: pyridine / dichloromethane / 3 h / 0 - 20 °C

4: sodium hydroxide / methanol; water / 0.5 h / 50 °C

With pyridine; bronze powder; palladium 10% on activated carbon; hydrogen; triethylamine; sodium hydroxide; In methanol; dichloromethane; water; ethyl acetate;
DOI:10.1016/j.bmc.2012.03.056

Reference yield:

: 1-benzyloxy-2-isopropylbenzene

: 373641-61-3
N-[4-(4-hydroxy-3-isopropylphenoxy)-2,3,5-trimethylphenyl]malonamic acid

Guidance literature:: Multi-step reaction with 5 steps

1.1: iodine tris(trifluoroacetate); acetic anhydride; trifluoroacetic acid / 16 h / 4 °C

1.2: 0.5 h

2.1: bronze powder; triethylamine / dichloromethane / 120 h / 20 °C

3.1: palladium 10% on activated carbon; hydrogen / water; ethyl acetate / 20 °C

4.1: pyridine / dichloromethane / 3 h / 0 - 20 °C

5.1: sodium hydroxide / methanol; water / 0.5 h / 50 °C

With pyridine; bronze powder; iodine tris(trifluoroacetate); palladium 10% on activated carbon; hydrogen; acetic anhydride; triethylamine; trifluoroacetic acid; sodium hydroxide; In methanol; dichloromethane; water; ethyl acetate;
DOI:10.1016/j.bmc.2012.03.056