2,3,4-tri-O-benzyl-6-O-p-nitrobenzoyl-α-D-glucopyranosyl bromide

Base Information

• Chemical Name: 2,3,4-tri-O-benzyl-6-O-p-nitrobenzoyl-α-D-glucopyranosyl bromide
• CAS No.: 39483-53-9
• Molecular Formula: C₃₄H₃₂BrNO₈
• Molecular Weight: 662.534
• Mol file: 39483-53-9.mol

Synonyms:2,3,4-tri-O-benzyl-6-O-p-nitrobenzoyl-α-D-glucopyranosyl bromide

Chemical Property of 2,3,4-tri-O-benzyl-6-O-p-nitrobenzoyl-α-D-glucopyranosyl bromide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,3,4-tri-O-benzyl-6-O-p-nitrobenzoyl-α-D-glucopyranosyl bromide

There total 1 articles about 2,3,4-tri-O-benzyl-6-O-p-nitrobenzoyl-α-D-glucopyranosyl bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 2,3,4-tri-O-benzyl-6-O-p-nitrobenzoyl-α-D-glucopyranosyl bromide (39483-53-9)

Guidance literature:

aus p-Nitrobenzoat I-1 mit Br2;

DOI:10.1246/cl.1972.1049

Reference yield: 85.0%

2,3,4-tri-O-benzyl-6-O-p-nitrobenzoyl-α-D-glucopyranosyl bromide (39483-53-9) + (S)-oxiranemethanol (60456-23-7) → (2R,3R,4S,5R,6S)-3,4,5-Tris-benzyloxy-2-(4-nitro-benzyloxymethyl)-6-((S)-1-oxiranylmethoxy)-tetrahydro-pyran (176911-83-4)

Guidance literature:

With tetramethylurea; In dichloromethane;

DOI:10.1016/S0040-4039(00)73526-X

Reference yield: 74.0%

2,3,4-tri-O-benzyl-6-O-p-nitrobenzoyl-α-D-glucopyranosyl bromide (39483-53-9) + methyl (6S)-(6-2H)-2,3-di-O-acetyl-4-O-(2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl)-β-D-glucopyranose → methyl (6S)-(6-2H)-2,3-di-O-acetyl-4-O-(2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl)-6-O-(2,3,4-tri-O-benzyl-6-O-p-nitrobenzoyl-α-D-glucopyranosyl)-β-D-glucopyranoside

Guidance literature:

With 4 A molecular sieve; tetraethylammonium bromide; In dichloromethane; N,N-dimethyl-formamide; for 36h; Ambient temperature;

Downstream raw materials:

(2R,3R,4S,5R,6S)-3,4,5-Tris-benzyloxy-2-(4-nitro-benzyloxymethyl)-6-((S)-1-oxiranylmethoxy)-tetrahydro-pyran

Hexadecanoic acid (S)-2-hydroxy-3-((2S,3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-propyl ester

Hexadecanoic acid (S)-1-hexadecanoyloxymethyl-2-((2S,3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-ethyl ester

Hexadecanoic acid (S)-1-hexadecanoyloxymethyl-2-[(2S,3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-pyran-2-yloxy]-ethyl ester