ethyl (S_S,2R,3S)-(+)-2-N-(diphenylmethyleneamino)-3-N-(p-toluenesulfinyl)amino-3-phenylpropanoate

Base Information

• Chemical Name: ethyl (S_S,2R,3S)-(+)-2-N-(diphenylmethyleneamino)-3-N-(p-toluenesulfinyl)amino-3-phenylpropanoate
• CAS No.: 930299-14-2
• Molecular Formula: C₃₁H₃₀N₂O₃S
• Molecular Weight: 510.657

Synonyms:ethyl (S_S,2R,3S)-(+)-2-N-(diphenylmethyleneamino)-3-N-(p-toluenesulfinyl)amino-3-phenylpropanoate

Chemical Property of ethyl (S_S,2R,3S)-(+)-2-N-(diphenylmethyleneamino)-3-N-(p-toluenesulfinyl)amino-3-phenylpropanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl (S_S,2R,3S)-(+)-2-N-(diphenylmethyleneamino)-3-N-(p-toluenesulfinyl)amino-3-phenylpropanoate

There total 5 articles about ethyl (S_S,2R,3S)-(+)-2-N-(diphenylmethyleneamino)-3-N-(p-toluenesulfinyl)amino-3-phenylpropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

ethyl N-diphenylmethylene glycine (69555-14-2) + (S,E)-N-benzylidene-4-methylbenzenesulfinamide (350479-90-2) → ethyl (SS,2R,3S)-(+)-2-N-(diphenylmethyleneamino)-3-N-(p-toluenesulfinyl)amino-3-phenylpropanoate (930299-14-2)

Guidance literature:

ethyl N-diphenylmethylene glycine; With lithium diisopropyl amide; In tetrahydrofuran; n-heptane; ethylbenzene; at -78 ℃; for 1h;

(S,E)-N-benzylidene-4-methylbenzenesulfinamide; In tetrahydrofuran; n-heptane; ethylbenzene; at -78 ℃; for 0.5h;

DOI:10.1021/ol063058c

Reference yield: 86.0%

ethyl N-diphenylmethylene glycine (69555-14-2) + (SS,2S,3S)-(+)-ethyl 2-N-(diphenylmethylideneamino)-3-N-(p-toluenesulfinyl)amino-3-phenylpropanoate (749253-91-6) → ethyl (SS,2R,3S)-(+)-2-N-(diphenylmethyleneamino)-3-N-(p-toluenesulfinyl)amino-3-phenylpropanoate (930299-14-2)

Guidance literature:

ethyl N-diphenylmethylene glycine; With lithium diisopropyl amide; In tetrahydrofuran; hexane; at -78 ℃; for 1h;

(S_S,2S,3S)-(+)-ethyl 2-N-(diphenylmethylideneamino)-3-N-(p-toluenesulfinyl)amino-3-phenylpropanoate; In tetrahydrofuran; hexane; at -78 ℃; for 1h;

DOI:10.1021/ol063058c

Reference yield:

ethyl N-diphenylmethylene glycine (69555-14-2) → ethyl (SS,2R,3S)-(+)-2-N-(diphenylmethyleneamino)-3-N-(p-toluenesulfinyl)amino-3-phenylpropanoate (930299-14-2)

Guidance literature:

Multi-step reaction with 2 steps

1.1: LDA; water / tetrahydrofuran; cyclohexane / 1 h / -78 °C

1.2: 86 percent / tetrahydrofuran; cyclohexane / 1.5 h / -78 °C

2.1: LDA / tetrahydrofuran; hexane / 1 h / -78 °C

2.2: 86 percent / tetrahydrofuran; hexane / 1 h / -78 °C

With water; lithium diisopropyl amide; In tetrahydrofuran; hexane; cyclohexane;

DOI:10.1021/ol063058c

upstream raw materials:

ethyl N-diphenylmethylene glycine

(S,E)-N-benzylidene-4-methylbenzenesulfinamide

(S_S,2S,3S)-(+)-ethyl 2-N-(diphenylmethylideneamino)-3-N-(p-toluenesulfinyl)amino-3-phenylpropanoate

Downstream raw materials:

(4R,5S)-(-)-ethyl 2-oxo-5-phenylimidazolidine-4-carboxylate

ethyl N-diphenylmethylene glycine

(S,E)-N-benzylidene-4-methylbenzenesulfinamide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 930299-14-2 ethyl (S_S,2R,3S)-(+)-2-N-(diphenylmethyleneamino)-3-N-(p-toluenesulfinyl)amino-3-phenylpropanoate

Send

Send

Metric Ton KG G Pound L ML

Send

Send