Neamine

Base Information

Chemical Name:Neamine
CAS No.:3947-65-7
Molecular Formula:C12H26 N4 O6
Molecular Weight:322.362
Hs Code.:
UNII:5981U00LY0
DSSTox Substance ID:DTXSID7023358
Nikkaji Number:J4.461J
Wikipedia:Neamine
Wikidata:Q6984256
NCI Thesaurus Code:C76155
Metabolomics Workbench ID:50011
ChEMBL ID:CHEMBL427409
Mol file:3947-65-7.mol

Synonyms:neamin;neamine;neomycin A

Suppliers and Price of Neamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Neamine
5mg
$ 333.00

TRC
Neamine
100mg
$ 435.00

Sigma-Aldrich
Neamine European Pharmacopoeia (EP) Reference Standard
$ 190.00

Sigma-Aldrich
Neamine European Pharmacopoeia (EP) Reference Standard
n0300000
$ 190.00

Medical Isotopes, Inc.
Neamine
250 mg
$ 550.00

Crysdot
(2R,3S,4R,5R,6R)-5-Amino-2-(aminomethyl)-6-(((1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl)oxy)tetrahydro-2H-pyran-3,4-diol 97%
5mg
$ 515.00

Biosynth Carbosynth
Neamine
100 mg
$ 650.00

Biosynth Carbosynth
Neamine
50 mg
$ 350.00

Biosynth Carbosynth
Neamine
10 mg
$ 92.00

Biosynth Carbosynth
Neamine
5 mg
$ 60.00

Total 47 raw suppliers

Chemical Property of Neamine

Chemical Property:

Vapor Pressure:9.19E-16mmHg at 25°C
Melting Point:225.5°C (rough estimate)
Refractive Index:1.6120 (estimate)
Boiling Point:577.9°C at 760 mmHg
PKA:13.24±0.70(Predicted)
Flash Point:303.3°C
PSA：203.46000
Density:1.51g/cm³
LogP:-2.31440
Storage Temp.:Hygroscopic, Refrigerator, Under inert atmosphere
Solubility.:Aqueous Acid (Slightly), Methanol (Slightly, Heated), Water (Slightly)
XLogP3:-5.4
Hydrogen Bond Donor Count:8
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:3
Exact Mass:322.18523456
Heavy Atom Count:22
Complexity:378

Purity/Quality:

97% ^*data from raw suppliers

Neamine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(C(C(C(C1N)OC2C(C(C(C(O2)CN)O)O)N)O)O)N
Isomeric SMILES:C1[C@H]([C@@H]([C@H]([C@@H]([C@H]1N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CN)O)O)N)O)O)N
Recent EU Clinical Trials:Monitoring the effectiveness and safety of biological drugs for treatment of psoriasis through evaluation of clinical and biological markers

Technology Process of Neamine

There total 20 articles about Neamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 549501-35-1
(1S,2R,3R,4S,6R)-4,6-Diamino-3-((2R,3R,4R,5R,6R)-3-amino-6-aminomethyl-4,5-bis-benzyloxy-tetrahydro-pyran-2-yloxy)-cyclohexane-1,2-diol

: 3947-65-7
neomycin A

Guidance literature:: With hydrogen; 20% palladium hydroxide on carbon; In water; acetic acid;

Reference yield: 82.0%

: 119-04-0
neomycin B

: 3947-65-7
neomycin A

Guidance literature:: With hydrogenchloride; In methanol; for 6h; Heating;
DOI:10.1021/ja9612817

Reference yield: 70.0%

: neomycin B trisulfate

: 3947-65-7
neomycin A

Guidance literature:: neomycin B trisulfate; With hydrogenchloride; In methanol; for 6h; Heating;

With ammonium hydroxide; ammonia; In methanol; Further stages.;
DOI:10.1021/jo0707636