C₂₅H₃₂O₇S

Base Information

• Chemical Name: C₂₅H₃₂O₇S
• CAS No.: 91186-27-5
• Molecular Formula: C₂₅H₃₂O₇S
• Molecular Weight: 476.591
• Mol file: 91186-27-5.mol

Synonyms:C₂₅H₃₂O₇S

Chemical Property of C₂₅H₃₂O₇S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₅H₃₂O₇S

There total 10 articles about C₂₅H₃₂O₇S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

(4aS,5R,7aR,8aS,9S,10S,12aS,12bR)-5-Benzenesulfonyl-10-methoxy-9,12a-dimethyl-decahydro-7-oxa-cyclopenta[k]phenanthrene-3,6-dione (90397-77-6) → C25H32O7S (91186-27-5)

Guidance literature:

With boron trifluoride diethyl etherate; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 25 ℃; for 18h;

DOI:10.1016/S0040-4039(01)90060-7

Reference yield: 88.0%

(4aS,5R,7aR,8aS,9S,10S,12aS,12bR)-5-Benzenesulfonyl-10-methoxy-9,12a-dimethyl-decahydro-7-oxa-cyclopenta[k]phenanthrene-3,6-dione (90397-77-6) → C25H32O7S (91186-27-5)

Guidance literature:

With boron trifluoride diethyl etherate; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; Ambient temperature;

DOI:10.1021/jo00356a030

Reference yield:

1-methyl-6-methoxy-2-tetralone (5111-67-1) → C25H32O7S (91186-27-5)

Guidance literature:

Multi-step reaction with 8 steps

1: 82 percent / K₂CO₃ / methanol / 48 h / Ambient temperature

2: 59 percent / lithium, ammonia / tetrahydrofuran; 2-methyl-propan-2-ol / 2 h / Heating

3: 1.) sodium hydride / 1.) THF, reflux, 1 h, 2.) THF, reflux, 1 h

4: 89 percent / pyridine, p-toluenesulfonic acid / CH₂Cl₂ / 1 h / Ambient temperature

5: 94 percent / NaHCO₃, oxone / tetrahydrofuran; dioxane; H₂O / 1 h / Ambient temperature

6: 90 percent / N,N'-dicyclohexylcarbodiimide (DCC) / CH₂Cl₂ / 2 h / Ambient temperature

7: 84 percent / cesium fluoride / acetonitrile / Ambient temperature

8: 88 percent / m-chloroperoxybenzoic acid, boron trifluoride etherate / CH₂Cl₂ / Ambient temperature

With pyridine; Oxone; boron trifluoride diethyl etherate; ammonia; lithium; sodium hydride; sodium hydrogencarbonate; potassium carbonate; toluene-4-sulfonic acid; 3-chloro-benzenecarboperoxoic acid; dicyclohexyl-carbodiimide; cesium fluoride; In tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane; water; acetonitrile; tert-butyl alcohol;

DOI:10.1021/jo00356a030

upstream raw materials:

(4aS,5R,7aR,8aS,9S,10S,12aS,12bR)-5-Benzenesulfonyl-10-methoxy-9,12a-dimethyl-decahydro-7-oxa-cyclopenta[k]phenanthrene-3,6-dione

(4aS,5R,7aR,8aS,9S,10S,12aS,12bR)-5-Benzenesulfonyl-10-methoxy-9,12a-dimethyl-decahydro-7-oxa-cyclopenta[k]phenanthrene-3,6-dione

1-methyl-6-methoxy-2-tetralone

2,3,4,4a,9,10-hexahydro-7-methoxy-1,4aβ-dimethyl-2-phenanthrone