C₁₄H₁₀O₃

Base Information

• Chemical Name: C₁₄H₁₀O₃
• CAS No.: 1448449-58-8
• Molecular Formula: C₁₄H₁₀O₃
• Molecular Weight: 226.232
• Mol file: 1448449-58-8.mol

Synonyms:C₁₄H₁₀O₃

Chemical Property of C₁₄H₁₀O₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₄H₁₀O₃

There total 7 articles about C₁₄H₁₀O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

2-[(1E)-2-(4-hydroxyphenyl)ethenyl]-1,4-benzenediol (1093198-83-4) → C14H10O3 (1448449-58-8)

Guidance literature:

With ammonium cerium (IV) nitrate; In water; acetonitrile; at 20 ℃; for 1h; Reagent/catalyst; Solvent;

DOI:10.1039/c3ob40962g

Reference yield:

C32H51BO4Si2 (1448449-56-6) → C14H10O3 (1448449-58-8)

Guidance literature:

Multi-step reaction with 3 steps

1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.25 h / 0 °C / Inert atmosphere

2: dihydrogen peroxide / aq. phosphate buffer / pH 8.3

3: ammonium cerium (IV) nitrate / acetonitrile; water / 1 h / 20 °C

With ammonium cerium (IV) nitrate; tetrabutyl ammonium fluoride; dihydrogen peroxide; In tetrahydrofuran; aq. phosphate buffer; water; acetonitrile;

DOI:10.1039/c3ob40962g

Reference yield:

(4-(bromomethyl)phenoxy) (tert-butyl) dimethylsilane (120506-39-0) → C14H10O3 (1448449-58-8)

Guidance literature:

Multi-step reaction with 5 steps

1.1: toluene / 2.5 h / 20 °C / Reflux

2.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 °C / Inert atmosphere

2.2: 2 h / 20 - 50 °C / Inert atmosphere

3.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.25 h / 0 °C / Inert atmosphere

4.1: dihydrogen peroxide / aq. phosphate buffer / pH 8.3

5.1: ammonium cerium (IV) nitrate / acetonitrile; water / 1 h / 20 °C

With n-butyllithium; ammonium cerium (IV) nitrate; tetrabutyl ammonium fluoride; dihydrogen peroxide; In tetrahydrofuran; aq. phosphate buffer; hexane; water; toluene; acetonitrile; 2.2: |Wittig Olefination;

DOI:10.1039/c3ob40962g

upstream raw materials:

C₃₂H₅₁BO₄Si₂

2-[(1E)-2-(4-hydroxyphenyl)ethenyl]-1,4-benzenediol

5-hydroxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde

2-bromo-5-hydroxybenzaldehyde