cis-4-hydroxy-6-methyl-3-(5-methyl-2-cyclohexen-1-yl)-2-pyrone

Base Information

• Chemical Name: cis-4-hydroxy-6-methyl-3-(5-methyl-2-cyclohexen-1-yl)-2-pyrone
• CAS No.: 116503-95-8
• Molecular Formula: C₁₃H₁₆O₃
• Molecular Weight: 220.268
• Mol file: 116503-95-8.mol

Synonyms:cis-4-hydroxy-6-methyl-3-(5-methyl-2-cyclohexen-1-yl)-2-pyrone

Chemical Property of cis-4-hydroxy-6-methyl-3-(5-methyl-2-cyclohexen-1-yl)-2-pyrone

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of cis-4-hydroxy-6-methyl-3-(5-methyl-2-cyclohexen-1-yl)-2-pyrone

There total 1 articles about cis-4-hydroxy-6-methyl-3-(5-methyl-2-cyclohexen-1-yl)-2-pyrone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 39.5%

4-hydroxy-6-methyl-2-pyron (675-10-5) + (RS,RS)-5-methylcyclohex-2-en-1-yl acetate (61221-47-4) → trans-4-hydroxy-6-methyl-3-(5-methyl-2-cyclohexen-1-yl)-2-pyrone (116503-96-9) + cis-4-hydroxy-6-methyl-3-(5-methyl-2-cyclohexen-1-yl)-2-pyrone (116503-95-8)

Guidance literature:

With bis(acetylacetonato)palladium(II); 1,8-diazabicyclo[5.4.0]undec-7-ene; triphenylphosphine; In toluene; at 80 ℃; for 2.5h;

DOI:10.1021/jo00257a023

Reference yield: 99.0%

cis-4-hydroxy-6-methyl-3-(5-methyl-2-cyclohexen-1-yl)-2-pyrone (116503-95-8) → cis-4-hydroxy-6-methyl-3-(3-methylcyclohexyl)-2-pyrone (116504-01-9)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol; under 760 Torr;

DOI:10.1021/jo00257a023

upstream raw materials:

4-hydroxy-6-methyl-2-pyron

(RS,RS)-5-methylcyclohex-2-en-1-yl acetate

Downstream raw materials:

cis-4-hydroxy-6-methyl-3-(3-methylcyclohexyl)-2-pyrone