(E)-tert-butyl 2-(3-(3-(4-(3-ethynylphenylamino)quinazolin-7-ylcarbamoyl)phenyl)acrylamido)phenylcarbamate

Base Information

Chemical Name:(E)-tert-butyl 2-(3-(3-(4-(3-ethynylphenylamino)quinazolin-7-ylcarbamoyl)phenyl)acrylamido)phenylcarbamate
CAS No.:1152132-03-0
Molecular Formula:C₃₇H₃₂N₆O₄
Molecular Weight:624.699
Hs Code.:

Synonyms:(E)-tert-butyl 2-(3-(3-(4-(3-ethynylphenylamino)quinazolin-7-ylcarbamoyl)phenyl)acrylamido)phenylcarbamate

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Chemical Property of (E)-tert-butyl 2-(3-(3-(4-(3-ethynylphenylamino)quinazolin-7-ylcarbamoyl)phenyl)acrylamido)phenylcarbamate

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Technology Process of (E)-tert-butyl 2-(3-(3-(4-(3-ethynylphenylamino)quinazolin-7-ylcarbamoyl)phenyl)acrylamido)phenylcarbamate

There total 1 articles about (E)-tert-butyl 2-(3-(3-(4-(3-ethynylphenylamino)quinazolin-7-ylcarbamoyl)phenyl)acrylamido)phenylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 183319-57-5
N⁴-(3-ethynylphenyl)quinazoline-4,7-diamine

: C₂₁H₂₁ClN₂O₄

: 1152132-03-0
(E)-tert-butyl 2-(3-(3-(4-(3-ethynylphenylamino)quinazolin-7-ylcarbamoyl)phenyl)acrylamido)phenylcarbamate

Guidance literature:: With pyridine; at 20 ℃; for 16h;

Reference yield: 63.0%

: 1152132-03-0
(E)-tert-butyl 2-(3-(3-(4-(3-ethynylphenylamino)quinazolin-7-ylcarbamoyl)phenyl)acrylamido)phenylcarbamate

: 1152132-04-1
(E)-3-(3-(2-aminophenylamino)-3-oxoprop-1-enyl)-N-(4-(3-ethynylphenylamino)quinazolin-7-yl)benzamide

Guidance literature:: (E)-tert-butyl 2-(3-(3-(4-(3-ethynylphenylamino)quinazolin-7-ylcarbamoyl)phenyl)acrylamido)phenylcarbamate; With formic acid; at 20 ℃;

With ammonia; In water; pH=9;