5-{4-[3-hydroxy-2-(3-methyl-pyridin-2-yl)propoxy]benzyl}-2,4-thiazolidinedione

Base Information

Chemical Name:5-{4-[3-hydroxy-2-(3-methyl-pyridin-2-yl)propoxy]benzyl}-2,4-thiazolidinedione
CAS No.:101930-99-8
Molecular Formula:C₁₉H₂₀N₂O₄S
Molecular Weight:372.445
Hs Code.:

Synonyms:5-{4-[3-hydroxy-2-(3-methyl-pyridin-2-yl)propoxy]benzyl}-2,4-thiazolidinedione

Suppliers and Price of 5-{4-[3-hydroxy-2-(3-methyl-pyridin-2-yl)propoxy]benzyl}-2,4-thiazolidinedione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 5-{4-[3-hydroxy-2-(3-methyl-pyridin-2-yl)propoxy]benzyl}-2,4-thiazolidinedione

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 5-{4-[3-hydroxy-2-(3-methyl-pyridin-2-yl)propoxy]benzyl}-2,4-thiazolidinedione

There total 6 articles about 5-{4-[3-hydroxy-2-(3-methyl-pyridin-2-yl)propoxy]benzyl}-2,4-thiazolidinedione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 5-<4-<3-Hydroxy-2-(3-methyl-2-pyridyl)propoxy>benzyl>-2-imino-4-thiazolidinone

: 101930-99-8
5-{4-[3-hydroxy-2-(3-methyl-pyridin-2-yl)propoxy]benzyl}-2,4-thiazolidinedione

Guidance literature:: With hydrogenchloride; Heating;

Reference yield:

: 127676-17-9
2-(3-Methyl-2-pyridyl)-1,3-propanediol

: 101930-99-8
5-{4-[3-hydroxy-2-(3-methyl-pyridin-2-yl)propoxy]benzyl}-2,4-thiazolidinedione

Guidance literature:: Multi-step reaction with 5 steps

1: 56 percent / NaH / dimethylformamide / 1 h

2: H₂ / 10percent Pd-C / methanol / 760 Torr / Ambient temperature

3: 1.)47percent HBr, NaNO₂, 2.)Cu₂O / 1.)MeOH, H₂O, 5 deg C, 20 min., 2.)40 deg C

4: 58 percent / NaOAc / ethanol / 3 h / Heating

5: 83 percent / 2N HCl / Heating

With copper(I) oxide; hydrogenchloride; hydrogen bromide; hydrogen; sodium acetate; sodium hydride; sodium nitrite; palladium on activated charcoal; In methanol; ethanol; N,N-dimethyl-formamide;

Reference yield:

: 127676-16-8
4-<3-Hydroxy-2-(3-methyl-2-pyridyl)-propoxy>nitrobenzene

: 101930-99-8
5-{4-[3-hydroxy-2-(3-methyl-pyridin-2-yl)propoxy]benzyl}-2,4-thiazolidinedione

Guidance literature:: Multi-step reaction with 4 steps

1: H₂ / 10percent Pd-C / methanol / 760 Torr / Ambient temperature

2: 1.)47percent HBr, NaNO₂, 2.)Cu₂O / 1.)MeOH, H₂O, 5 deg C, 20 min., 2.)40 deg C

3: 58 percent / NaOAc / ethanol / 3 h / Heating

4: 83 percent / 2N HCl / Heating

With copper(I) oxide; hydrogenchloride; hydrogen bromide; hydrogen; sodium acetate; sodium nitrite; palladium on activated charcoal; In methanol; ethanol;