(R_S)-N-acetyl-N-((E)-cinnamyl)-2-methylpropane-2-sulfinamide

Base Information

• Chemical Name: (R_S)-N-acetyl-N-((E)-cinnamyl)-2-methylpropane-2-sulfinamide
• CAS No.: 1607465-59-7
• Molecular Formula: C₁₅H₂₁NO₂S
• Molecular Weight: 279.403
• Mol file: 1607465-59-7.mol

Synonyms:(R_S)-N-acetyl-N-((E)-cinnamyl)-2-methylpropane-2-sulfinamide

Chemical Property of (R_S)-N-acetyl-N-((E)-cinnamyl)-2-methylpropane-2-sulfinamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R_S)-N-acetyl-N-((E)-cinnamyl)-2-methylpropane-2-sulfinamide

There total 1 articles about (R_S)-N-acetyl-N-((E)-cinnamyl)-2-methylpropane-2-sulfinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

(RS)-N-acetyl-tert-butanesulfinamide (1360831-17-9) + (E)-methyl cinnamyl carbonate (87802-71-9,85217-69-2) → (RS)-N-acetyl-N-((E)-cinnamyl)-2-methylpropane-2-sulfinamide (1607465-59-7)

Guidance literature:

With palladium diacetate; 1,2-bis-(diphenylphosphino)ethane; In tetrahydrofuran; at 70 ℃; regioselective reaction; Inert atmosphere; Sealed tube;

DOI:10.1016/j.jorganchem.2013.11.026

Reference yield: 99.0%

(RS)-N-acetyl-N-((E)-cinnamyl)-2-methylpropane-2-sulfinamide (1607465-59-7) → (E)-3-Acetamido-1-phenylprop-1-ene (120990-24-1)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; methanol; at 0 ℃; for 2h;

DOI:10.1016/j.jorganchem.2013.11.026

Reference yield: 79.0%

(RS)-N-acetyl-N-((E)-cinnamyl)-2-methylpropane-2-sulfinamide (1607465-59-7) → (RS)-N-(cinnamyl)-2-methylpropane-2-sulfinamide (1361129-89-6)

Guidance literature:

With sodium hydroxide; In methanol; for 4h; Reflux;

DOI:10.1016/j.jorganchem.2013.11.026

upstream raw materials:

(R_S)-N-acetyl-tert-butanesulfinamide

(E)-methyl cinnamyl carbonate

Downstream raw materials:

(R_S)-N-(cinnamyl)-2-methylpropane-2-sulfinamide

(E)-3-Acetamido-1-phenylprop-1-ene