(2S,4S,5S)-2-(6-benzyloxy-2-methoxymethoxy-3,5-dimethylhexyl)-3,5,6-trimethoxy-4-methylbenzaldehyde

Base Information

Chemical Name:(2S,4S,5S)-2-(6-benzyloxy-2-methoxymethoxy-3,5-dimethylhexyl)-3,5,6-trimethoxy-4-methylbenzaldehyde
CAS No.:845536-42-7
Molecular Formula:C₂₈H₄₀O₇
Molecular Weight:488.621
Hs Code.:

Synonyms:(2S,4S,5S)-2-(6-benzyloxy-2-methoxymethoxy-3,5-dimethylhexyl)-3,5,6-trimethoxy-4-methylbenzaldehyde

Suppliers and Price of (2S,4S,5S)-2-(6-benzyloxy-2-methoxymethoxy-3,5-dimethylhexyl)-3,5,6-trimethoxy-4-methylbenzaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,4S,5S)-2-(6-benzyloxy-2-methoxymethoxy-3,5-dimethylhexyl)-3,5,6-trimethoxy-4-methylbenzaldehyde

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,4S,5S)-2-(6-benzyloxy-2-methoxymethoxy-3,5-dimethylhexyl)-3,5,6-trimethoxy-4-methylbenzaldehyde

There total 6 articles about (2S,4S,5S)-2-(6-benzyloxy-2-methoxymethoxy-3,5-dimethylhexyl)-3,5,6-trimethoxy-4-methylbenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 845536-41-6
(2S,4S,5S)-1-benzyloxy-5-methoxymethoxy-2,4-dimethyl-6-(2,4,5-trimethoxy-3-methyl-6-bromophenyl)hexane

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 845536-42-7
(2S,4S,5S)-2-(6-benzyloxy-2-methoxymethoxy-3,5-dimethylhexyl)-3,5,6-trimethoxy-4-methylbenzaldehyde

Guidance literature:: With tert.-butyl lithium; In diethyl ether; at -78 - -10 ℃;
DOI:10.1021/ol047779s

Reference yield:

: 845536-34-7
(3S,4S,6S)-7-benzyloxy-3-methoxymethoxy-4,6-dimethylheptanal

: 845536-42-7
(2S,4S,5S)-2-(6-benzyloxy-2-methoxymethoxy-3,5-dimethylhexyl)-3,5,6-trimethoxy-4-methylbenzaldehyde

Guidance literature:: Multi-step reaction with 5 steps

1.1: 87 percent / tert-BuOK / tetrahydrofuran; propan-2-ol / 1 h / -78 - 20 °C

2.1: tert-BuLi / diethyl ether / -78 - 20 °C

2.2: H₂O

2.3: air / tetrahydrofuran / 19 h / 20 - 50 °C

3.1: 94 percent / K₂CO₃ / acetone / 12 h / 40 °C

4.1: 85 percent / NBS / dimethylformamide / 16 h / 20 °C

5.1: 80 percent / tert-BuLi / diethyl ether / -78 - -10 °C

With N-Bromosuccinimide; potassium tert-butylate; tert.-butyl lithium; potassium carbonate; In tetrahydrofuran; diethyl ether; N,N-dimethyl-formamide; isopropyl alcohol; acetone; 2.3: Doetz reaction;
DOI:10.1021/ol047779s

Reference yield:

: (2R,4S,5RS)-(5-methoxymethoxy-2,4-dimethyloct-7-enyloxymethyl)benzene

: 845536-42-7
(2S,4S,5S)-2-(6-benzyloxy-2-methoxymethoxy-3,5-dimethylhexyl)-3,5,6-trimethoxy-4-methylbenzaldehyde

Guidance literature:: Multi-step reaction with 6 steps

1.1: O₃ / CH₂Cl₂; methanol / -78 °C

1.2: 88 percent / Ph₃P / methanol; CH₂Cl₂ / 3 h / -78 - 20 °C

2.1: 87 percent / tert-BuOK / tetrahydrofuran; propan-2-ol / 1 h / -78 - 20 °C

3.1: tert-BuLi / diethyl ether / -78 - 20 °C

3.2: H₂O

3.3: air / tetrahydrofuran / 19 h / 20 - 50 °C

4.1: 94 percent / K₂CO₃ / acetone / 12 h / 40 °C

5.1: 85 percent / NBS / dimethylformamide / 16 h / 20 °C

6.1: 80 percent / tert-BuLi / diethyl ether / -78 - -10 °C

With N-Bromosuccinimide; potassium tert-butylate; tert.-butyl lithium; potassium carbonate; ozone; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; N,N-dimethyl-formamide; isopropyl alcohol; acetone; 3.3: Doetz reaction;
DOI:10.1021/ol047779s