(6S,13S)-13-((E)-4-tritylsulfanyl-but-1-enyl)-6-tritylsulfanylmethyl-14-oxa-4,7,10,17-tetraaza-spiro[2.15]octadecane-5,8,11,15,18-pentaone

Base Information

Chemical Name:(6S,13S)-13-((E)-4-tritylsulfanyl-but-1-enyl)-6-tritylsulfanylmethyl-14-oxa-4,7,10,17-tetraaza-spiro[2.15]octadecane-5,8,11,15,18-pentaone
CAS No.:1196992-61-6
Molecular Formula:C₅₆H₅₄N₄O₆S₂
Molecular Weight:943.2
Hs Code.:

Synonyms:(6S,13S)-13-((E)-4-tritylsulfanyl-but-1-enyl)-6-tritylsulfanylmethyl-14-oxa-4,7,10,17-tetraaza-spiro[2.15]octadecane-5,8,11,15,18-pentaone

Suppliers and Price of (6S,13S)-13-((E)-4-tritylsulfanyl-but-1-enyl)-6-tritylsulfanylmethyl-14-oxa-4,7,10,17-tetraaza-spiro[2.15]octadecane-5,8,11,15,18-pentaone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (6S,13S)-13-((E)-4-tritylsulfanyl-but-1-enyl)-6-tritylsulfanylmethyl-14-oxa-4,7,10,17-tetraaza-spiro[2.15]octadecane-5,8,11,15,18-pentaone

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (6S,13S)-13-((E)-4-tritylsulfanyl-but-1-enyl)-6-tritylsulfanylmethyl-14-oxa-4,7,10,17-tetraaza-spiro[2.15]octadecane-5,8,11,15,18-pentaone

There total 8 articles about (6S,13S)-13-((E)-4-tritylsulfanyl-but-1-enyl)-6-tritylsulfanylmethyl-14-oxa-4,7,10,17-tetraaza-spiro[2.15]octadecane-5,8,11,15,18-pentaone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

: 1196992-59-2
[(1-{(S)-2-[2-((E)-(S)-3-hydroxy-7-tritylsulfanyl-hept-4-enoylamino)-acetylamino]-3-tritylsulfanyl-propionylamino}-cyclopropanecarbonyl)-amino]-acetic acid

: 1196992-61-6
(6S,13S)-13-((E)-4-tritylsulfanyl-but-1-enyl)-6-tritylsulfanylmethyl-14-oxa-4,7,10,17-tetraaza-spiro[2.15]octadecane-5,8,11,15,18-pentaone

Guidance literature:: With dmap; 2-methyl-6-nitrobenzoic anhydride; In dichloromethane; at 20 ℃;

Reference yield:

: 180973-24-4
(E)-(S)-3-hydroxy-7-tritylthio-4-heptenoic acid

: 1196992-61-6
(6S,13S)-13-((E)-4-tritylsulfanyl-but-1-enyl)-6-tritylsulfanylmethyl-14-oxa-4,7,10,17-tetraaza-spiro[2.15]octadecane-5,8,11,15,18-pentaone

Guidance literature:: Multi-step reaction with 3 steps

1.1: diethylamine / acetonitrile / 2 h / 20 °C / Inert atmosphere

1.2: 16 h / 20 °C / Inert atmosphere

2.1: water; lithium hydroxide / tetrahydrofuran / 0 °C

3.1: dmap; 2-methyl-6-nitrobenzoic anhydride / dichloromethane / 20 °C

With dmap; 2-methyl-6-nitrobenzoic anhydride; water; diethylamine; lithium hydroxide; In tetrahydrofuran; dichloromethane; acetonitrile;

Reference yield:

: 167015-11-4
Fmoc-D-Cys(Trt)-OH

: 1196992-61-6
(6S,13S)-13-((E)-4-tritylsulfanyl-but-1-enyl)-6-tritylsulfanylmethyl-14-oxa-4,7,10,17-tetraaza-spiro[2.15]octadecane-5,8,11,15,18-pentaone

Guidance literature:: Multi-step reaction with 5 steps

1.1: diethylamine / acetonitrile / 1 h / 20 °C

1.2: 0 - 20 °C

2.1: diethylamine / dichloromethane; acetonitrile / 1.83 h / 20 °C / Inert atmosphere

2.2: 16 h / 20 °C / Inert atmosphere

3.1: diethylamine / acetonitrile / 2 h / 20 °C / Inert atmosphere

3.2: 16 h / 20 °C / Inert atmosphere

4.1: water; lithium hydroxide / tetrahydrofuran / 0 °C

5.1: dmap; 2-methyl-6-nitrobenzoic anhydride / dichloromethane / 20 °C

With dmap; 2-methyl-6-nitrobenzoic anhydride; water; diethylamine; lithium hydroxide; In tetrahydrofuran; dichloromethane; acetonitrile;