(1Z,3Z)-1,3-bis{[(S)-4-phenyl-4,5-dihydrooxazol-2-yl]methylene}isoindoline

Base Information

Chemical Name:(1Z,3Z)-1,3-bis{[(S)-4-phenyl-4,5-dihydrooxazol-2-yl]methylene}isoindoline
CAS No.:1358991-52-2
Molecular Formula:C₂₈H₂₃N₃O₂
Molecular Weight:433.51
Hs Code.:

Synonyms:(1Z,3Z)-1,3-bis{[(S)-4-phenyl-4,5-dihydrooxazol-2-yl]methylene}isoindoline

Suppliers and Price of (1Z,3Z)-1,3-bis{[(S)-4-phenyl-4,5-dihydrooxazol-2-yl]methylene}isoindoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of (1Z,3Z)-1,3-bis{[(S)-4-phenyl-4,5-dihydrooxazol-2-yl]methylene}isoindoline

Chemical Property:

Purity/Quality:: 98%+ ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1Z,3Z)-1,3-bis{[(S)-4-phenyl-4,5-dihydrooxazol-2-yl]methylene}isoindoline

There total 3 articles about (1Z,3Z)-1,3-bis{[(S)-4-phenyl-4,5-dihydrooxazol-2-yl]methylene}isoindoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 1361563-30-5
C₂₈H₂₇N₃O₄

: 1358991-52-2,1429056-54-1
(1Z,3Z)-1,3-bis{[(S)-4-phenyl-4,5-dihydrooxazol-2-yl]methylene}isoindoline

Guidance literature:: With tetrachloromethane; triethylamine; triphenylphosphine; In acetonitrile; at 20 ℃; Inert atmosphere;
DOI:10.1002/chem.201102375

Reference yield:

: 136918-14-4,85-41-6
phthalimide

: 1358991-52-2,1429056-54-1
(1Z,3Z)-1,3-bis{[(S)-4-phenyl-4,5-dihydrooxazol-2-yl]methylene}isoindoline

Guidance literature:: Multi-step reaction with 3 steps

1: 5 h / 140 °C / Inert atmosphere

2: sodium hydride / 7 h / 120 °C / Inert atmosphere

3: tetrachloromethane; triethylamine; triphenylphosphine / acetonitrile / 20 °C / Inert atmosphere

With tetrachloromethane; sodium hydride; triethylamine; triphenylphosphine; In acetonitrile; 1: Wittig reaction;
DOI:10.1002/chem.201102375

Reference yield:

: 20989-17-7
(2S)-2-phenylglycinol

: 26191-42-4
1,3-Bis-isoindolin

: 1358991-52-2,1429056-54-1
(1Z,3Z)-1,3-bis{[(S)-4-phenyl-4,5-dihydrooxazol-2-yl]methylene}isoindoline

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydride / 7 h / 120 °C / Inert atmosphere

2: tetrachloromethane; triethylamine; triphenylphosphine / acetonitrile / 20 °C / Inert atmosphere

With tetrachloromethane; sodium hydride; triethylamine; triphenylphosphine; In acetonitrile;
DOI:10.1002/chem.201102375