4-(2-(4-ethynylphenyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl)pyridin-2(1H)-one

Base Information

Chemical Name:4-(2-(4-ethynylphenyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl)pyridin-2(1H)-one
CAS No.:1620085-51-9
Molecular Formula:C₂₂H₁₄FN₃O
Molecular Weight:355.371
Hs Code.:

Synonyms:4-(2-(4-ethynylphenyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl)pyridin-2(1H)-one

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-(2-(4-ethynylphenyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl)pyridin-2(1H)-one

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Technology Process of 4-(2-(4-ethynylphenyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl)pyridin-2(1H)-one

There total 1 articles about 4-(2-(4-ethynylphenyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl)pyridin-2(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1620085-50-8
1-(4-fluorophenyl)-2-(2-oxo-1,2-dihydropyridin-4-yl)ethane-1,2-dione

: 63697-96-1
4-Ethynylbenzaldehyde

: 1620085-51-9
4-(2-(4-ethynylphenyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl)pyridin-2(1H)-one

Guidance literature:: With ammonium acetate; acetic acid; at 180 ℃; for 0.166667h; Microwave irradiation;
DOI:10.1016/j.bmcl.2014.05.080

Reference yield:

: 637-81-0
ethyl-2-azidoacetate

: 1620085-51-9
4-(2-(4-ethynylphenyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl)pyridin-2(1H)-one

: 1620085-53-1
C₂₆H₂₁FN₆O₃

Guidance literature:: With copper(II) sulfate penta hydrate; sodium L-ascorbate; In ethanol; water; at 20 ℃; for 18h; regioselective reaction;
DOI:10.1016/j.bmcl.2014.05.080

Reference yield:

: 1620085-51-9
4-(2-(4-ethynylphenyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl)pyridin-2(1H)-one

: 196302-98-4
2-azidoethylphosphonic acid diethyl ester

: 1620085-54-2
diethyl (2-(4-(4-(4-(4-fluorophenyl)-5-(2-oxo-1,2-dihydropyridin-4-yl)-1H-imidazol-2-yl)phenyl)-1H-1,2,3-triazol-1-yl)ethyl)phosphonate

Guidance literature:: With copper(II) sulfate penta hydrate; sodium L-ascorbate; In ethanol; water; at 20 - 80 ℃; regioselective reaction;
DOI:10.1016/j.bmcl.2014.05.080