AZD₃₇₈₃

Base Information

Chemical Name:AZD₃₇₈₃
CAS No.:1162658-64-1
Molecular Formula:C₂₆H₃₄N₄O₄
Molecular Weight:466.58
Hs Code.:

Synonyms:AZD₃₇₈₃

Suppliers and Price of AZD₃₇₈₃

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of AZD₃₇₈₃

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of AZD₃₇₈₃

There total 2 articles about AZD₃₇₈₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: (+)-6-methoxy-8-(4-methyl-piperazin-1-yl)-chroman-2-carboxylic acid hydrochloride

: 2524-67-6,86759-37-7
4-morpholino-4-yl-phenylamine

: 1162658-64-1
AZD₃₇₈₃

Guidance literature:: With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃;

Reference yield: 13.0%

: 936023-99-3,936024-00-9,936024-01-0
(+/-)6-methoxy-8-(4-methyl-piperazin-1-yl)-N-(4-morpholin-4-yl-phenyl)chroman-2-carboxamide

: (-)-6-methoxy-8-(4-methyl-piperazin-1-yl)-N-(4-morpholin-4-yl-phenyl)chroman-2-carboxamide

: 1162658-64-1
AZD₃₇₈₃

Guidance literature:: Purification / work up; Resolution of racemate;

Reference yield:

: 1162658-64-1
AZD₃₇₈₃

: 3,4-dihydro-6-methoxy-8-(4-methylpiperazin-1-yl)-N-(4-morpholino-[2,6-⁽³⁾H₂]phenyl)-2H-chromene-2-carboxamide

Guidance literature:: With tritium; [(1R)-1-[bis(4-methoxy-3,5-dimethylphenyl)phosphino-κP]-2-[(1R)-1-(dicyclohexylphosphino-κP)ethyl]ferrocene][(1,2,5,6-η)-1,5-cyclooctadiene]iridium tetrafluoroborate; In dichloromethane; at 20 ℃; under 162.016 Torr;
DOI:10.1002/jlcr.1534