N-benzoyl>-β-alanine benzyl ester

Base Information

• Chemical Name: N-benzoyl>-β-alanine benzyl ester
• CAS No.: 138108-62-0
• Molecular Formula: C₂₃H₂₇N₃O₅
• Molecular Weight: 425.484
• Mol file: 138108-62-0.mol

Synonyms:N-benzoyl>-β-alanine benzyl ester

Chemical Property of N-benzoyl>-β-alanine benzyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of N-benzoyl>-β-alanine benzyl ester

There total 4 articles about N-benzoyl>-β-alanine benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-(aminoiminomethyl)benzoic acid (15535-95-2) → N-benzoyl>-β-alanine benzyl ester (138108-62-0)

Guidance literature:

Multi-step reaction with 3 steps

1: thionyl chloride / tetrahydrofuran; dimethylformamide / 20 °C

2: aq. NaHCO₃ / CH₂Cl₂ / 3.5 h

3: aq. Na₂CO₃ / CH₂Cl₂

With thionyl chloride; sodium hydrogencarbonate; sodium carbonate; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1021/jm00101a017

Reference yield:

4-amidinobenzoyl chloride hydrochloride → N-benzoyl>-β-alanine benzyl ester (138108-62-0)

Guidance literature:

Multi-step reaction with 2 steps

1: aq. NaHCO₃ / CH₂Cl₂ / 3.5 h

2: aq. Na₂CO₃ / CH₂Cl₂

With sodium hydrogencarbonate; sodium carbonate; In dichloromethane;

DOI:10.1021/jm00101a017

Reference yield:

di-tert-butyl dicarbonate (24424-99-5) + 3-(4-Carbamimidoyl-benzoylamino)-propionic acid benzyl ester → N-benzoyl>-β-alanine benzyl ester (138108-62-0)

Guidance literature:

With sodium carbonate; In dichloromethane; Yield given;

DOI:10.1021/jm00101a017

upstream raw materials:

di-tert-butyl dicarbonate

4-(aminoiminomethyl)benzoic acid

Downstream raw materials:

N-benzoyl>-β-alanine

benzyl (S)-3-<benzoyl>-β-alanyl>amino>-3-<(p-methoxyphenethyl)carbamoyl>propionate