ethyl 2-(cyclopent-1-enecarbonyl)-4-nitro-3-phenylbutanoate

Base Information

• Chemical Name: ethyl 2-(cyclopent-1-enecarbonyl)-4-nitro-3-phenylbutanoate
• CAS No.: 1266754-78-2
• Molecular Formula: C₁₈H₂₁NO₅
• Molecular Weight: 331.368
• Mol file: 1266754-78-2.mol

Synonyms:ethyl 2-(cyclopent-1-enecarbonyl)-4-nitro-3-phenylbutanoate

Chemical Property of ethyl 2-(cyclopent-1-enecarbonyl)-4-nitro-3-phenylbutanoate

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of ethyl 2-(cyclopent-1-enecarbonyl)-4-nitro-3-phenylbutanoate

There total 1 articles about ethyl 2-(cyclopent-1-enecarbonyl)-4-nitro-3-phenylbutanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2-nitroethenyl)benzene (102-96-5) + 3-Oxo-3--propionsaeureaethylester (26395-19-7) → ethyl 2-(cyclopent-1-enecarbonyl)-4-nitro-3-phenylbutanoate (1266754-78-2)

Guidance literature:

(2-nitroethenyl)benzene; With 9-O-benzyl-6'-hydroxycinchonidine; In dichloromethane; at 30 ℃; for 0.5h;

3-Oxo-3--propionsaeureaethylester; In dichloromethane; at 0 ℃; for 20h; stereoselective reaction;

DOI:10.1021/ol1029832

Reference yield:

ethyl 2-(cyclopent-1-enecarbonyl)-4-nitro-3-phenylbutanoate (1266754-78-2) → ethyl 4-hydroxy-7-nitro-6-phenyl-2,3,3a,6,7,7a-hexahydro-1H-indene-5-carboxylate (1266754-29-3)

Guidance literature:

With N,N,N',N'-tetramethylguanidine; In dichloromethane; at 0 ℃; for 20h; optical yield given as %ee; stereospecific reaction;

DOI:10.1021/ol1029832

upstream raw materials:

(2-nitroethenyl)benzene

3-Oxo-3--propionsaeureaethylester

Downstream raw materials:

ethyl 4-hydroxy-7-nitro-6-phenyl-2,3,3a,6,7,7a-hexahydro-1H-indene-5-carboxylate