5-Phenyl-[1,3,4]oxadiazol-2-YL-methylamine

Base Information

• Chemical Name: 5-Phenyl-[1,3,4]oxadiazol-2-YL-methylamine
• CAS No.: 22377-39-5
• Molecular Formula: C₉H₉N₃O
• Molecular Weight: 175.19
• European Community (EC) Number: 960-245-2
• Nikkaji Number: J1.569.358D

Synonyms:5-PHENYL-[1,3,4]OXADIAZOL-2-YL-METHYLAMINE;N-methyl-5-phenyl-1,3,4-oxadiazol-2-amine;22377-39-5;SCHEMBL6676849;AKOS023624322;EN300-6683933;Methyl-(5-phenyl-[1,3,4]oxadiazol-2-yl)-amine;Z1509142797

Chemical Property of 5-Phenyl-[1,3,4]oxadiazol-2-YL-methylamine

Chemical Property:

• XLogP3: 1.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 175.074561919
• Heavy Atom Count: 13
• Complexity: 159

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CNC1=NN=C(O1)C2=CC=CC=C2

Technology Process of 5-Phenyl-[1,3,4]oxadiazol-2-YL-methylamine

There total 11 articles about 5-Phenyl-[1,3,4]oxadiazol-2-YL-methylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

1-(phenyl)carbonyl-4-(methyl)thiosemicarbazide (58064-65-6) → methyl-(5-phenyl-[1,3,4]oxadiazol-2-yl)-amine (22377-39-5)

Guidance literature:

With acetic acid; ethanaminium,N-(difluoro-λ⁴-sulfanylidene)-N-ethyl-,tetrafluoroborate; In 1,2-dichloro-ethane; at 90 ℃; for 12h; Inert atmosphere;

DOI:10.1039/c1ob06512b

Reference yield: 61.0%

4-methylthiosemicarbazide (6610-29-3) + benzoic acid (65-85-0,8013-63-6) → methyl-(5-phenyl-[1,3,4]oxadiazol-2-yl)-amine (22377-39-5)

Guidance literature:

With resin-based EDCI; In N,N-dimethyl-formamide; for 12h;

DOI:10.1016/j.tetlet.2008.09.057

Reference yield: 50.0%

1-benzylidene-4-methylsemicarbazide (40848-87-1) → methyl-(5-phenyl-[1,3,4]oxadiazol-2-yl)-amine (22377-39-5)

Guidance literature:

With lead dioxide; In formic acid; for 0.333333h; Ambient temperature;

upstream raw materials:

1-benzoyl-4,S-dimethyl-iso thiosemicarbazide

1-benzylidene-4-methylsemicarbazide

N-methyl-N-(5-phenyl-[1,3,4]oxadiazol-2-yl)-acetamide

3-methylamino-5-phenyl-1,2,4-oxadiazole

Downstream raw materials:

N-methyl-N-(5-phenyl-[1,3,4]oxadiazol-2-yl)-benzamide

methyl-(3-methyl-5-phenyl-3H-[1,3,4]oxadiazol-2-ylidene)-amine

methyl-nitroso-(5-phenyl-[1,3,4]oxadiazol-2-yl)-amine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 22377-39-5 methyl-(5-phenyl-[1,3,4]oxadiazol-2-yl)-amine

Send

Send

Metric Ton KG G Pound L ML

Send

Send