(E)-2-(3-Methoxy-phenoxymethyl)-3-(4-methoxy-phenyl)-acrylic acid

Base Information

• Chemical Name: (E)-2-(3-Methoxy-phenoxymethyl)-3-(4-methoxy-phenyl)-acrylic acid
• CAS No.: 214000-07-4
• Molecular Formula: C₁₈H₁₈O₅
• Molecular Weight: 314.338
• Mol file: 214000-07-4.mol

Synonyms:(E)-2-(3-Methoxy-phenoxymethyl)-3-(4-methoxy-phenyl)-acrylic acid

Chemical Property of (E)-2-(3-Methoxy-phenoxymethyl)-3-(4-methoxy-phenyl)-acrylic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-2-(3-Methoxy-phenoxymethyl)-3-(4-methoxy-phenyl)-acrylic acid

There total 3 articles about (E)-2-(3-Methoxy-phenoxymethyl)-3-(4-methoxy-phenyl)-acrylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

(E)-2-(3-Methoxy-phenoxymethyl)-3-(4-methoxy-phenyl)-acrylic acid methyl ester (214000-05-2) → (E)-2-(3-Methoxy-phenoxymethyl)-3-(4-methoxy-phenyl)-acrylic acid (214000-07-4)

Guidance literature:

With potassium hydroxide; water; In acetone; for 14h; Ambient temperature;

DOI:10.1039/a804796k

Reference yield:

O-methylresorcine (150-19-6) → (E)-2-(3-Methoxy-phenoxymethyl)-3-(4-methoxy-phenyl)-acrylic acid (214000-07-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 60 percent / K₂CO₃ / acetone / 3 h / Heating

2: 94 percent / H₂O, KOH / acetone / 14 h / Ambient temperature

With potassium hydroxide; water; potassium carbonate; In acetone;

DOI:10.1039/a804796k

Reference yield:

methyl (2Z)-2-(bromomethyl)-3-(4-methoxyphenyl)prop-2-enoate (213999-88-3) → (E)-2-(3-Methoxy-phenoxymethyl)-3-(4-methoxy-phenyl)-acrylic acid (214000-07-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 60 percent / K₂CO₃ / acetone / 3 h / Heating

2: 94 percent / H₂O, KOH / acetone / 14 h / Ambient temperature

With potassium hydroxide; water; potassium carbonate; In acetone;

DOI:10.1039/a804796k

upstream raw materials:

(E)-2-(3-Methoxy-phenoxymethyl)-3-(4-methoxy-phenyl)-acrylic acid methyl ester

O-methylresorcine

methyl (2Z)-2-(bromomethyl)-3-(4-methoxyphenyl)prop-2-enoate

Downstream raw materials:

(3E)-2,3-dihydro-7-methoxy-3-[(4-methoxyphenyl)-methylene]-4H-1-benzopyran-4-one