(2S,3S)-(-)-1,4-di-O-isopropylidene-3-phenylthio-1,2,4-butanetriol

Base Information

• Chemical Name: (2S,3S)-(-)-1,4-di-O-isopropylidene-3-phenylthio-1,2,4-butanetriol
• CAS No.: 174691-31-7
• Molecular Formula: C₁₃H₁₈O₃S
• Molecular Weight: 254.35
• Mol file: 174691-31-7.mol

Synonyms:(2S,3S)-(-)-1,4-di-O-isopropylidene-3-phenylthio-1,2,4-butanetriol

Chemical Property of (2S,3S)-(-)-1,4-di-O-isopropylidene-3-phenylthio-1,2,4-butanetriol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2S,3S)-(-)-1,4-di-O-isopropylidene-3-phenylthio-1,2,4-butanetriol

There total 3 articles about (2S,3S)-(-)-1,4-di-O-isopropylidene-3-phenylthio-1,2,4-butanetriol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane (57280-22-5) → (2S,3S)-(-)-1,4-di-O-isopropylidene-3-phenylthio-1,2,4-butanetriol (174691-31-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 96.9 percent / NaH / tetrahydrofuran / 0 deg C, 30 min, reflux, 1 h

With sodium hydride; In tetrahydrofuran;

DOI:10.1055/s-1995-4090

Reference yield:

thiophenol (108-98-5) → (2S,3S)-(-)-1,4-di-O-isopropylidene-3-phenylthio-1,2,4-butanetriol (174691-31-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 96.9 percent / NaH / tetrahydrofuran / 0 deg C, 30 min, reflux, 1 h

With sodium hydride; In tetrahydrofuran;

DOI:10.1055/s-1995-4090

Reference yield:

(2R*,3R*)-1,4-di-O-isopropylidene-3-phenylthio-1,2,4-butanetriol → (2S,3S)-(-)-1,4-di-O-isopropylidene-3-phenylthio-1,2,4-butanetriol (174691-31-7)

Guidance literature:

DOI:10.1055/s-1995-4090

upstream raw materials:

4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]-octane

thiophenol

Downstream raw materials:

(2S,3S)-3-phenylthio-1,2,4-butanetriol