Technology Process of 1-(6-chloro-1-tosyl-1H-pyrrolo[3,2-b]pyridin-5-yl)ethanone oxime
There total 6 articles about 1-(6-chloro-1-tosyl-1H-pyrrolo[3,2-b]pyridin-5-yl)ethanone oxime which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
hydroxylamine hydrochloride; sodium acetate;
In
ethanol;
at 20 ℃;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 2 h / 20 °C / Cooling with ice
2.1: N,N-Dimethylcarbamoyl chloride / 1,2-dichloro-ethane / 80 °C / Inert atmosphere
3.1: tetrahydrofuran / 1.5 h / -10 - 0 °C / Inert atmosphere
3.2: Inert atmosphere
4.1: hydroxylamine hydrochloride; sodium acetate / ethanol / 20 °C
With
hydroxylamine hydrochloride; sodium acetate; 3-chloro-benzenecarboperoxoic acid; N,N-Dimethylcarbamoyl chloride;
In
tetrahydrofuran; ethanol; dichloromethane; 1,2-dichloro-ethane;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: N,N-Dimethylcarbamoyl chloride / 1,2-dichloro-ethane / 80 °C / Inert atmosphere
2.1: tetrahydrofuran / 1.5 h / -10 - 0 °C / Inert atmosphere
2.2: Inert atmosphere
3.1: hydroxylamine hydrochloride; sodium acetate / ethanol / 20 °C
With
hydroxylamine hydrochloride; sodium acetate; N,N-Dimethylcarbamoyl chloride;
In
tetrahydrofuran; ethanol; 1,2-dichloro-ethane;