Nordefrin

Base Information

• Chemical Name: Nordefrin
• CAS No.: 6539-57-7
• Deprecated CAS: 99-38-7,547-42-2,16275-43-7,20291-28-5,3005-41-2,36505-65-4,37612-67-2,6209-07-0
• Molecular Formula: C9H13 N O3
• Molecular Weight: 183.207
• Hs Code.: 2922509090
• European Community (EC) Number: 229-452-9
• DSSTox Substance ID: DTXSID10859546
• Nikkaji Number: J8.423I
• Wikidata: Q27155324
• NCI Thesaurus Code: C81340,C99670
• Metabolomics Workbench ID: 144396
• ChEMBL ID: CHEMBL764
• Mol file: 6539-57-7.mol

Synonyms:3,4 Dihydroxynorephedrine;3,4-Dihydroxynorephedrine;4-(2-Amino-1-hydroxypropyl)-1,2-benzenediol;4-(2-Amino-1-hydroxypropyl)-1,2-benzenediol Hydrochloride, (R*,R*)-(+,-)-Isomer;4-(2-Amino-1-hydroxypropyl)-1,2-benzenediol Hydrochloride, (R*,S*)-(+-)-Isomer;4-(2-Amino-1-hydroxypropyl)-1,2-benzenediol Tartrate, (R*,R*), (R*,R*)-Isomer;4-(2-Amino-1-hydroxypropyl)-1,2-benzenediol Tartrate, (R*,S*), (R*,R*)-Isomer;4-(2-Amino-1-hydroxypropyl)-1,2-benzenediol, (R*,R*)-Isomer;4-(2-Amino-1-hydroxypropyl)-1,2-benzenediol, (R*,S*)-Isomer;alpha Methylnoradrenaline;alpha Methylnorepinephrine;alpha-Methylnoradrenaline;alpha-Methylnorepinephrine;Cobefrine;Corbadrine;Hydrochloride, Nordefrin;Levonordefrin;Methylnorepinephrine;Neo Cobefrin;Neo-Cobefrin;NeoCobefrin;Nordefrin;Nordefrin Hydrochloride;Nordefrin Hydrochloride, (R*,R*)-(+,-)-Isomer;Nordefrin Hydrochloride, (R*,S*)-(+,-)-Isomer;Nordefrin Tartrate, (R*,R*), (R*,R*) Isomer;Nordefrin Tartrate, (R*,S*), (R*,R*) Isomer;Nordefrin, (R*,R*)-Isomer;Nordefrin, (R*,S*)-Isomer;Norephrine

Chemical Property of Nordefrin

Chemical Property:

• Vapor Pressure: 3.25E-08mmHg at 25°C
• Melting Point: 220 °C (decomp)
• Boiling Point: 431.6°C at 760 mmHg
• PKA: 9.59±0.10(Predicted)
• Flash Point: 214.8°C
• PSA: 86.71000
• Density: 1.328g/cm³
• LogP: 1.17870
• XLogP3: -0.8
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 183.08954328
• Heavy Atom Count: 13
• Complexity: 165

Purity/Quality:

ALPHA-METHYLNORADRENALINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C(C1=CC(=C(C=C1)O)O)O)N

Technology Process of Nordefrin

There total 2 articles about Nordefrin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ Isoadrenaline (6539-57-7,18829-78-2)

Guidance literature:

entspr. α-Oximinoketon, Tritiumgas;

Reference yield:

→ threo-2-amino-1-(3.4-dihydroxy-phenyl)-propanol-(1) (829-74-3,829-75-4,6539-57-7,16202-33-8,16906-82-4,20521-15-7,20727-99-5,74812-63-8,18829-78-2)

Guidance literature:

With methanol; palladium on activated charcoal; Hydrogenation;