ethyl 4-(3,4-dichlorophenyl)-1-(prop-2-enyl)-piperidine-4-carboxylate

Base Information

• Chemical Name: ethyl 4-(3,4-dichlorophenyl)-1-(prop-2-enyl)-piperidine-4-carboxylate
• CAS No.: 864755-37-3
• Molecular Formula: C₁₇H₂₁Cl₂NO₂
• Molecular Weight: 342.265
• Mol file: 864755-37-3.mol

Synonyms:ethyl 4-(3,4-dichlorophenyl)-1-(prop-2-enyl)-piperidine-4-carboxylate

Chemical Property of ethyl 4-(3,4-dichlorophenyl)-1-(prop-2-enyl)-piperidine-4-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of ethyl 4-(3,4-dichlorophenyl)-1-(prop-2-enyl)-piperidine-4-carboxylate

There total 1 articles about ethyl 4-(3,4-dichlorophenyl)-1-(prop-2-enyl)-piperidine-4-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-(3,4-dichlorophenyl)-1-methylpiperidine-4-carboxylic acid ethyl ester (258500-91-3) → ethyl 4-(3,4-dichlorophenyl)-1-(prop-2-enyl)-piperidine-4-carboxylate (864755-37-3)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium hydrocarbonate; 1-chloro-ethylchloroformate / 1,2-dichloro-ethane / 48 h / Heating

2: 136 mg / potassium iodide; triethylamine / ethanol / 16 h / Heating

With carbonochloridic acid 1-chloro-ethyl ester; sodium hydrogencarbonate; triethylamine; potassium iodide; In ethanol; 1,2-dichloro-ethane;

DOI:10.1016/j.bmc.2005.05.025

Reference yield: 56.0%

ethyl 4-(3,4-dichlorophenyl)-1-(prop-2-enyl)-piperidine-4-carboxylate (864755-37-3) → ethyl 4-(3,4-dichlorophenyl)-1-propyl-piperidine-4-carboxylate

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol; under 760 Torr;

DOI:10.1016/j.bmc.2005.05.025

upstream raw materials:

4-(3,4-dichlorophenyl)-1-methylpiperidine-4-carboxylic acid ethyl ester