Technology Process of 2-deoxy-3,5-di-O-p-toluoyl-D-erythro-pentosyl chloride-2,2',3,4-2H4
There total 10 articles about 2-deoxy-3,5-di-O-p-toluoyl-D-erythro-pentosyl chloride-2,2',3,4-2H4 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 9 steps
1: 33 percent / deuterium oxide / deuterated Raney nickel / 15 h / Heating
2: 90 percent / p-toluenesulfonic acid monohydrate / dimethylformamide / 3 h / 20 °C
3: 86 percent / N,N-dimethylaminopyridine / acetonitrile / 20 °C
4: tri-n-butyltin-deuteride, 2,2'-azo-bis-(2-methylpropionitrile) / toluene / 2 h / 80 °C
5: 80percent acetic acid / 15 h / 20 °C
6: 0.5 M HCl / 40 h / 20 °C
7: HCl
8: pyridine
9: 60 percent / HCl / acetic acid
With
pyridine; hydrogenchloride; dmap; 2,2'-azobis(isobutyronitrile); water-d2; tributyltin deuteride; toluene-4-sulfonic acid; acetic acid;
deuterated Raney nickel;
In
acetic acid; N,N-dimethyl-formamide; toluene; acetonitrile;
DOI:10.1016/S0040-4020(01)83465-7
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 86 percent / N,N-dimethylaminopyridine / acetonitrile / 20 °C
2: tri-n-butyltin-deuteride, 2,2'-azo-bis-(2-methylpropionitrile) / toluene / 2 h / 80 °C
3: 80percent acetic acid / 15 h / 20 °C
4: 0.5 M HCl / 40 h / 20 °C
5: HCl
6: pyridine
7: 60 percent / HCl / acetic acid
With
pyridine; hydrogenchloride; dmap; 2,2'-azobis(isobutyronitrile); tributyltin deuteride; acetic acid;
In
acetic acid; toluene; acetonitrile;
DOI:10.1016/S0040-4020(01)83465-7
