N⁴-(2-(diethylamino)ethyl)-2-iodo-N¹-(4-methyl-1-(4-methyl-1-(4-methyl-1-oxopentan-2-ylamino)-1-oxopentan-2-ylamino)-1-oxopentan-2-yl)terephthalamide

Base Information

• Chemical Name: N⁴-(2-(diethylamino)ethyl)-2-iodo-N¹-(4-methyl-1-(4-methyl-1-(4-methyl-1-oxopentan-2-ylamino)-1-oxopentan-2-ylamino)-1-oxopentan-2-yl)terephthalamide
• CAS No.: 1013658-07-5
• Molecular Formula: C₃₄H₅₇IN₆O₆
• Molecular Weight: 770.863

Synonyms:N⁴-(2-(diethylamino)ethyl)-2-iodo-N¹-(4-methyl-1-(4-methyl-1-(4-methyl-1-oxopentan-2-ylamino)-1-oxopentan-2-ylamino)-1-oxopentan-2-yl)terephthalamide

Chemical Property of N⁴-(2-(diethylamino)ethyl)-2-iodo-N¹-(4-methyl-1-(4-methyl-1-(4-methyl-1-oxopentan-2-ylamino)-1-oxopentan-2-ylamino)-1-oxopentan-2-yl)terephthalamide

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Technology Process of N⁴-(2-(diethylamino)ethyl)-2-iodo-N¹-(4-methyl-1-(4-methyl-1-(4-methyl-1-oxopentan-2-ylamino)-1-oxopentan-2-ylamino)-1-oxopentan-2-yl)terephthalamide

There total 1 articles about N⁴-(2-(diethylamino)ethyl)-2-iodo-N¹-(4-methyl-1-(4-methyl-1-(4-methyl-1-oxopentan-2-ylamino)-1-oxopentan-2-ylamino)-1-oxopentan-2-yl)terephthalamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

(E)-N4-(2-(diethylamino)ethyl)-N1-(1-(1-(1-(methoxy(methyl)amino)-4-methyl-1-oxopentan-2-ylamino)-4-methyl-1-oxopentan-2-ylamino)-4-methyl-1-oxopentan-2-yl)-2-(pyrrolidin-1-yldiazenyl)terephthalamide (1013658-00-8) → N4-(2-(diethylamino)ethyl)-2-iodo-N1-(4-methyl-1-(4-methyl-1-(4-methyl-1-oxopentan-2-ylamino)-1-oxopentan-2-ylamino)-1-oxopentan-2-yl)terephthalamide (1013658-07-5)

Guidance literature:

With sodium (12?I)iodide; trifluoroacetic acid; sodium iodide; In acetonitrile; at 20 ℃;

DOI:10.1021/jm701419g

Reference yield: 68.0%

N4-(2-(diethylamino)ethyl)-2-iodo-N1-(4-methyl-1-(4-methyl-1-(4-methyl-1-oxopentan-2-ylamino)-1-oxopentan-2-ylamino)-1-oxopentan-2-yl)terephthalamide (1013658-07-5) → N4-(2-(diethylamino)ethyl)-2-iodo-N1-(4-methyl-1-(4-methyl-1-(4-methyl-1-oxopentan-2-ylamino)-1-oxopentan-2-ylamino)-1-oxopentan-2-yl)terephthalamide (1013658-09-7)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; diethyl ether; at -80 - 0 ℃;

DOI:10.1021/jm701419g

upstream raw materials:

(E)-N⁴-(2-(diethylamino)ethyl)-N¹-(1-(1-(1-(methoxy(methyl)amino)-4-methyl-1-oxopentan-2-ylamino)-4-methyl-1-oxopentan-2-ylamino)-4-methyl-1-oxopentan-2-yl)-2-(pyrrolidin-1-yldiazenyl)terephthalamide

Downstream raw materials:

N⁴-(2-(diethylamino)ethyl)-2-iodo-N¹-(4-methyl-1-(4-methyl-1-(4-methyl-1-oxopentan-2-ylamino)-1-oxopentan-2-ylamino)-1-oxopentan-2-yl)terephthalamide

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