3-chloro-5-((1-((4-((4-methoxybenzyl)oxy)-2-(methylsulfonyl)pyrimidin-5-yl)methyl)-6-oxo-4-(trifluoromethyl)-1,6-dihydropyrimidin-5-yl)oxy)benzonitrile

Base Information

Chemical Name:3-chloro-5-((1-((4-((4-methoxybenzyl)oxy)-2-(methylsulfonyl)pyrimidin-5-yl)methyl)-6-oxo-4-(trifluoromethyl)-1,6-dihydropyrimidin-5-yl)oxy)benzonitrile
CAS No.:1591828-35-1
Molecular Formula:C₂₆H₁₉ClF₃N₅O₆S
Molecular Weight:621.981
Hs Code.:

3-chloro-5-((1-((4-((4-methoxybenzyl)oxy)-2-(methylsulfonyl)pyrimidin-5-yl)methyl)-6-oxo-4-(trifluoromethyl)-1,6-dihydropyrimidin-5-yl)oxy)benzonitrile

Synonyms:3-chloro-5-((1-((4-((4-methoxybenzyl)oxy)-2-(methylsulfonyl)pyrimidin-5-yl)methyl)-6-oxo-4-(trifluoromethyl)-1,6-dihydropyrimidin-5-yl)oxy)benzonitrile

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Chemical Property of 3-chloro-5-((1-((4-((4-methoxybenzyl)oxy)-2-(methylsulfonyl)pyrimidin-5-yl)methyl)-6-oxo-4-(trifluoromethyl)-1,6-dihydropyrimidin-5-yl)oxy)benzonitrile

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Technology Process of 3-chloro-5-((1-((4-((4-methoxybenzyl)oxy)-2-(methylsulfonyl)pyrimidin-5-yl)methyl)-6-oxo-4-(trifluoromethyl)-1,6-dihydropyrimidin-5-yl)oxy)benzonitrile

There total 11 articles about 3-chloro-5-((1-((4-((4-methoxybenzyl)oxy)-2-(methylsulfonyl)pyrimidin-5-yl)methyl)-6-oxo-4-(trifluoromethyl)-1,6-dihydropyrimidin-5-yl)oxy)benzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1591828-33-9
3-chloro-5-((1-((4-((4-methoxybenzyl)oxy)-2-(methylthio)pyrimidin-5-yl)methyl)-6-oxo-4-(trifluoromethyl)-1,6-dihydropyrimidin-5-yl)oxy)benzonitrile

: 1591828-35-1
3-chloro-5-((1-((4-((4-methoxybenzyl)oxy)-2-(methylsulfonyl)pyrimidin-5-yl)methyl)-6-oxo-4-(trifluoromethyl)-1,6-dihydropyrimidin-5-yl)oxy)benzonitrile

Guidance literature:: With 3-chloro-benzenecarboperoxoic acid; In dichloromethane;

Reference yield:

: 1591826-98-0
5-bromo-3-(4-methoxybenzyl)-6-(trifluoromethyl)pyrimidin-4(3H)-one

: 1591828-35-1
3-chloro-5-((1-((4-((4-methoxybenzyl)oxy)-2-(methylsulfonyl)pyrimidin-5-yl)methyl)-6-oxo-4-(trifluoromethyl)-1,6-dihydropyrimidin-5-yl)oxy)benzonitrile

Guidance literature:: Multi-step reaction with 4 steps

1: potassium carbonate

2: acetonitrile; water

3: triphenylphosphine; diethylazodicarboxylate / dichloromethane

4: 3-chloro-benzenecarboperoxoic acid / dichloromethane

With potassium carbonate; 3-chloro-benzenecarboperoxoic acid; triphenylphosphine; diethylazodicarboxylate; In dichloromethane; water; acetonitrile;

Reference yield:

: 1591826-99-1
3-chloro-5-(1-(4-methoxybenzyl)-6-oxo-4-(trifluoromethyl)-1,6-dihydropyrimidin-5-yloxy)benzonitrile

: 1591828-35-1
3-chloro-5-((1-((4-((4-methoxybenzyl)oxy)-2-(methylsulfonyl)pyrimidin-5-yl)methyl)-6-oxo-4-(trifluoromethyl)-1,6-dihydropyrimidin-5-yl)oxy)benzonitrile

Guidance literature:: Multi-step reaction with 3 steps

1: acetonitrile; water

2: triphenylphosphine; diethylazodicarboxylate / dichloromethane

3: 3-chloro-benzenecarboperoxoic acid / dichloromethane

With 3-chloro-benzenecarboperoxoic acid; triphenylphosphine; diethylazodicarboxylate; In dichloromethane; water; acetonitrile;