marasmic acid

Base Information

Chemical Name:marasmic acid
CAS No.:2212-99-9
Molecular Formula:C₁₅H₁₈O₄
Molecular Weight:262.306
Hs Code.:
Mol file:2212-99-9.mol

Synonyms:3H,6H-3a,8b-Methano-1H-indeno[4,5-c]furan-4-carboxaldehyde,5a,7,8,8a-tetrahydro-3-hydroxy-7,7-dimethyl-1-oxo-, [3S-(3a,3ab,5ab,8ab,8bb)]-; Marasmic acid (7CI,8CI); NSC 318506

Suppliers and Price of marasmic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
MARASMIC ACID 95.00%
5MG
$ 505.93

Total 7 raw suppliers

Chemical Property of marasmic acid

Chemical Property:

Vapor Pressure:1.52E-11mmHg at 25°C
Melting Point:173.5°C
Refractive Index:1.4350 (estimate)
Boiling Point:487.4°Cat760mmHg
PKA:11.22±0.60(Predicted)
Flash Point:187.7°C
PSA：63.60000
Density:1.34g/cm³
LogP:1.42940

Purity/Quality:

99% ^*data from raw suppliers

MARASMIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of marasmic acid

There total 45 articles about marasmic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 75918-37-5
(+/-)-methyl marasmate

: 2212-99-9,28417-28-9,61216-74-8,77698-81-8,123485-30-3,123485-31-4
(+/-)-marasmic acid

Guidance literature:: With boron tribromide; In dichloromethane; at -20 - 0 ℃; for 4.5h;
DOI:10.1021/ja00543a063

Reference yield:

: 2213-00-5,26575-49-5,75918-37-5,75918-38-6,77698-80-7
(1aR,3aR,6aS,6bS)-1a,2-Diformyl-5,5-dimethyl-1a,3a,4,5,6,6a-hexahydro-1H-cyclopropa[e]indene-6b-carboxylic acid methyl ester

: 2212-99-9,28417-28-9,61216-74-8,77698-81-8,123485-30-3,123485-31-4
(+/-)-marasmic acid

Guidance literature:: With boron tribromide; In dichloromethane; at -20 - 0 ℃; for 4.5h;
DOI:10.1021/ja00543a063

Reference yield:

: 61934-55-2
3-bromomethyl-2-butenolide

: 2212-99-9,28417-28-9,61216-74-8,77698-81-8,123485-30-3,123485-31-4
(+/-)-marasmic acid

Guidance literature:: Multi-step reaction with 10 steps

1: 90 percent / Heating

2: 80 percent / NaH / dimethylformamide / 0.5 h / -5 - 0 °C

3: 2.) KO-t-Bu / 1.) toluene, 200 deg C, 0.5 h, 2.) ether, 0 deg C, 0.5 h

4: p-TsOH / methanol / 12 h / 65 °C

5: NEt₃ / CH₂Cl₂ / 0.5 h / -5 °C

6: DBU / tetrahydrofuran / 8 h / 65 °C

7: 92 percent / 2 h / Ambient temperature

8: 95 percent / DIBAL-H / toluene; tetrahydrofuran / 12 h / -78 °C

9: MCPBA / 1.) CH₂Cl₂, -78 deg C, 2.) -78 deg C -> room temperature, 4.5 h

10: 50 percent / BBr₃ / CH₂Cl₂ / 4.5 h / -20 - 0 °C

With potassium tert-butylate; boron tribromide; sodium hydride; diisobutylaluminium hydride; toluene-4-sulfonic acid; 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide; toluene;
DOI:10.1021/ja00543a063