4-(4-(Phenylsulfonyl)-2-(thiophen-2-yl)oxazol-5-yl)morpholine

Base Information

• Chemical Name: 4-(4-(Phenylsulfonyl)-2-(thiophen-2-yl)oxazol-5-yl)morpholine
• CAS No.: 7065-27-2
• Molecular Formula: C11H10 O
• Molecular Weight: 158.2
• DSSTox Substance ID: DTXSID00361345
• Wikidata: Q82143642

Synonyms:4-(4-(phenylsulfonyl)-2-(thiophen-2-yl)oxazol-5-yl)morpholine;627832-80-8;7065-27-2;4-[4-(benzenesulfonyl)-2-thiophen-2-yl-1,3-oxazol-5-yl]morpholine;F3140-0010;4-[4-(BENZENESULFONYL)-2-(THIOPHEN-2-YL)-1,3-OXAZOL-5-YL]MORPHOLINE;DTXSID00361345;STK875092;AKOS001705573;NCGC00307113-01;AB00363091-02;SR-01000285948;SR-01000285948-1;4-[4-(phenylsulfonyl)-2-(thiophen-2-yl)-1,3-oxazol-5-yl]morpholine

Chemical Property of 4-(4-(Phenylsulfonyl)-2-(thiophen-2-yl)oxazol-5-yl)morpholine

Chemical Property:

• Vapor Pressure: 4.64E-15mmHg at 25°C
• Boiling Point: 615°Cat760mmHg
• Flash Point: 325.8°C
• Density: 1.384g/cm³
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 4
• Exact Mass: 376.05514934
• Heavy Atom Count: 25
• Complexity: 541

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1COCCN1C2=C(N=C(O2)C3=CC=CS3)S(=O)(=O)C4=CC=CC=C4

Technology Process of 4-(4-(Phenylsulfonyl)-2-(thiophen-2-yl)oxazol-5-yl)morpholine

There total 7 articles about 4-(4-(Phenylsulfonyl)-2-(thiophen-2-yl)oxazol-5-yl)morpholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

chloroacetone (78-95-5) + phenylacetylene (536-74-3) → 2-methyl-2-(2-phenylethynyl)oxirane (7065-27-2)

Guidance literature:

phenylacetylene; With n-butyllithium; In tetrahydrofuran; at -30 ℃; for 0.5h; Inert atmosphere;

chloroacetone; In tetrahydrofuran; at -78 - 20 ℃; for 24.1667h; Inert atmosphere;

DOI:10.1002/chem.201404903

Reference yield:

→ 2-methyl-2-(2-phenylethynyl)oxirane (7065-27-2)

Guidance literature:

With potassium hydroxide; diethyl ether;

DOI:10.1021/ja01185a053

Reference yield:

(3-methylbut-3-en-1-ynyl)benzene (1463-04-3) → 2-methyl-2-(2-phenylethynyl)oxirane (7065-27-2)

Guidance literature:

With Na₂HPO₄; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 0 ℃; for 3h;

DOI:10.1002/ejoc.200700963

upstream raw materials:

chloroacetone

lithium phenylacetylide

trimethylsulfoxonium iodide

4-phenyl-3-butyne-2-one

Downstream raw materials:

2-methyl-4-phenyl-but-3-ynal

4-methyl-2-phenylpyrrole

1-ethyl-4-methyl-2-phenyl-pyrrole

2-(4-methyl-2-phenyl-pyrrol-1-yl)-ethanol

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 7065-27-2 4-[4-(phenylsulfonyl)-2-(thiophen-2-yl)-1,3-oxazol-5-yl]morpholine

Send

Send

Metric Ton KG G Pound L ML

Send

Send