4-Hydroxy-5-phenyl-valeric acid

Base Information

• Chemical Name: 4-Hydroxy-5-phenyl-valeric acid
• CAS No.: 174720-07-1
• Molecular Formula: C₁₁H₁₄O₃
• Molecular Weight: 194.23
• DSSTox Substance ID: DTXSID301009410
• Mol file: 174720-07-1.mol

Synonyms:4-hydroxy-5-phenyl-valeric acid;174720-07-1;SCHEMBL6495924;DTXSID301009410;4-hydroxy-5-(phenyl)-valeric acid;AKOS010915047

Chemical Property of 4-Hydroxy-5-phenyl-valeric acid

Chemical Property:

• XLogP3: 1.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 194.094294304
• Heavy Atom Count: 14
• Complexity: 173

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C=C1)CC(CCC(=O)O)O

Technology Process of 4-Hydroxy-5-phenyl-valeric acid

There total 1 articles about 4-Hydroxy-5-phenyl-valeric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-oxo-5-phenylvaleric acid (3183-15-1) → 5-phenyl-γ-hydroxyvaleric acid (174720-07-1)

Guidance literature:

With sodium amalgam;

Reference yield:

5-phenyl-γ-hydroxyvaleric acid (174720-07-1) → (±)-5-benzyldihydrofuran-2(3H)-one (21175-42-8)

Guidance literature:

With hydrogenchloride; at 20 ℃; for 0.5h;

DOI:10.1016/j.tetasy.2006.11.020

Reference yield:

5-phenyl-γ-hydroxyvaleric acid (174720-07-1) → 4-hydroxy-N,N-dimethyl-5-phenylpentanamide (924893-87-8)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrochloric acid / 0.5 h / 20 °C

2: 94 percent / ethanol / 20 °C

With hydrogenchloride; In ethanol;

DOI:10.1016/j.tetasy.2006.11.020

upstream raw materials:

4-oxo-5-phenylvaleric acid

Downstream raw materials:

(±)-5-benzyldihydrofuran-2(3H)-one

4-hydroxy-N,N-dimethyl-5-phenylpentanamide