methyl 3-carboxy-2-((4'-methoxyphenyl)amino)-4-phenyl-4-(trimethylsilyl)butanoate

Base Information

Chemical Name:methyl 3-carboxy-2-((4'-methoxyphenyl)amino)-4-phenyl-4-(trimethylsilyl)butanoate
CAS No.:132377-60-7
Molecular Formula:C₂₂H₂₉NO₅Si
Molecular Weight:415.561
Hs Code.:

Synonyms:methyl 3-carboxy-2-((4'-methoxyphenyl)amino)-4-phenyl-4-(trimethylsilyl)butanoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of methyl 3-carboxy-2-((4'-methoxyphenyl)amino)-4-phenyl-4-(trimethylsilyl)butanoate

Chemical Property:

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Technology Process of methyl 3-carboxy-2-((4'-methoxyphenyl)amino)-4-phenyl-4-(trimethylsilyl)butanoate

There total 2 articles about methyl 3-carboxy-2-((4'-methoxyphenyl)amino)-4-phenyl-4-(trimethylsilyl)butanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 128474-82-8,128571-94-8
cis-anti-4-(methoxycarbonyl)-1-(4'-methoxyphenyl)-3-<1'-(trimethylsilyl)benzyl>azetidin-2-one

: 132377-60-7
methyl 3-carboxy-2-((4'-methoxyphenyl)amino)-4-phenyl-4-(trimethylsilyl)butanoate

Guidance literature:: With HBF₄*2Et₂O; In dichloromethane; for 24h; Ambient temperature;
DOI:10.1021/jo00006a053

Reference yield:

: 128474-82-8,128571-94-8
cis-syn-4-(methoxycarbonyl)-1-(4'-methoxyphenyl)-3-<1'-(trimethylsilyl)benzyl>azetidin-2-one

: 132377-60-7
(2S,3S)-2-(4-Methoxy-phenylamino)-3-((R)-phenyl-trimethylsilanyl-methyl)-succinic acid 1-methyl ester

Guidance literature:: With HBF₄*2Et₂O; In dichloromethane; for 24h; Ambient temperature;
DOI:10.1021/jo00006a053

Reference yield:

: 132377-60-7
methyl 3-carboxy-2-((4'-methoxyphenyl)amino)-4-phenyl-4-(trimethylsilyl)butanoate

: 128474-82-8,128571-94-8
cis-anti-4-(methoxycarbonyl)-1-(4'-methoxyphenyl)-3-<1'-(trimethylsilyl)benzyl>azetidin-2-one

Guidance literature:: With O-phenyl phosphorodichloridate; triethylamine; In acetonitrile; for 25h; Ambient temperature;
DOI:10.1021/jo00006a053