Technology Process of N-(3-bromo-3-fluoropropyl)-N-phenylbenzenesulfonamide
There total 5 articles about N-(3-bromo-3-fluoropropyl)-N-phenylbenzenesulfonamide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tetraethylammonium bromide;
In
chloroform;
Reflux;
Inert atmosphere;
DOI:10.1021/jacs.5b00473
- Guidance literature:
-
Multi-step reaction with 4 steps
1: lithium chloride / dimethyl sulfoxide; water / Reflux; Inert atmosphere
2: lithium hydroxide / tetrahydrofuran; water / 20 °C / Inert atmosphere
3: 1,3-diiodo-5,5-dimethylhydantoin / 1,2-dichloro-ethane / Irradiation; Inert atmosphere
4: tetraethylammonium bromide / chloroform / Reflux; Inert atmosphere
With
1,3-diiodo-5,5-dimethylhydantoin; tetraethylammonium bromide; lithium chloride; lithium hydroxide;
In
tetrahydrofuran; chloroform; water; dimethyl sulfoxide; 1,2-dichloro-ethane;
DOI:10.1021/jacs.5b00473
- Guidance literature:
-
Multi-step reaction with 5 steps
1: sodium hydride; Selectfluor / tetrahydrofuran / 20 °C / Inert atmosphere
2: lithium chloride / dimethyl sulfoxide; water / Reflux; Inert atmosphere
3: lithium hydroxide / tetrahydrofuran; water / 20 °C / Inert atmosphere
4: 1,3-diiodo-5,5-dimethylhydantoin / 1,2-dichloro-ethane / Irradiation; Inert atmosphere
5: tetraethylammonium bromide / chloroform / Reflux; Inert atmosphere
With
1,3-diiodo-5,5-dimethylhydantoin; tetraethylammonium bromide; sodium hydride; Selectfluor; lithium chloride; lithium hydroxide;
In
tetrahydrofuran; chloroform; water; dimethyl sulfoxide; 1,2-dichloro-ethane;
DOI:10.1021/jacs.5b00473
