benzyl N--Fmoc--(2S)--2--amino--6--(6--phenylhexanamido)hexanoate

Base Information

Chemical Name:benzyl N--Fmoc--(2S)--2--amino--6--(6--phenylhexanamido)hexanoate
CAS No.:1415221-98-5
Molecular Formula:C₄₀H₄₄N₂O₅
Molecular Weight:632.8
Hs Code.:

Synonyms:benzyl N--Fmoc--(2S)--2--amino--6--(6--phenylhexanamido)hexanoate

Suppliers and Price of benzyl N--Fmoc--(2S)--2--amino--6--(6--phenylhexanamido)hexanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of benzyl N--Fmoc--(2S)--2--amino--6--(6--phenylhexanamido)hexanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of benzyl N--Fmoc--(2S)--2--amino--6--(6--phenylhexanamido)hexanoate

There total 2 articles about benzyl N--Fmoc--(2S)--2--amino--6--(6--phenylhexanamido)hexanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5581-75-9
6-phenylhexanic acid

: 236404-46-9
N^α-Fmoc-Lys-OBzl

: 1415221-98-5
benzyl N--Fmoc--(2S)--2--amino--6--(6--phenylhexanamido)hexanoate

Guidance literature:: N^α-Fmoc-Lys-OBzl; With benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; HATU; In dichloromethane; at 0 ℃; for 0.5h; Inert atmosphere;

6-phenylhexanic acid; In dichloromethane; at 0 - 20 ℃; Inert atmosphere;
DOI:10.1016/j.bmcl.2012.10.093

Reference yield:

: 159541-28-3
(S)-6-tert-butoxycarbonylamino-2-(9H-fluoren-9-ylmethoxycarbonylamino)hexanoic acid benzyl ester

: 1415221-98-5
benzyl N--Fmoc--(2S)--2--amino--6--(6--phenylhexanamido)hexanoate

Guidance literature:: Multi-step reaction with 2 steps

1.1: trifluoroacetic acid / dichloromethane / 1 h / 20 °C

2.1: HATU; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine / dichloromethane / 0.5 h / 0 °C / Inert atmosphere

2.2: 0 - 20 °C / Inert atmosphere

With benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; HATU; trifluoroacetic acid; In dichloromethane;
DOI:10.1016/j.bmcl.2012.10.093