(S)-2,6-Bis-(2,2,2-trifluoro-acetylamino)-hexanoic acid [2-(4-vinyl-benzylcarbamoyl)-ethyl]-amide

Base Information

Chemical Name:(S)-2,6-Bis-(2,2,2-trifluoro-acetylamino)-hexanoic acid [2-(4-vinyl-benzylcarbamoyl)-ethyl]-amide
CAS No.:849586-31-8
Molecular Formula:C₂₂H₂₆F₆N₄O₄
Molecular Weight:524.463
Hs Code.:

Synonyms:(S)-2,6-Bis-(2,2,2-trifluoro-acetylamino)-hexanoic acid [2-(4-vinyl-benzylcarbamoyl)-ethyl]-amide

Suppliers and Price of (S)-2,6-Bis-(2,2,2-trifluoro-acetylamino)-hexanoic acid [2-(4-vinyl-benzylcarbamoyl)-ethyl]-amide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-2,6-Bis-(2,2,2-trifluoro-acetylamino)-hexanoic acid [2-(4-vinyl-benzylcarbamoyl)-ethyl]-amide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-2,6-Bis-(2,2,2-trifluoro-acetylamino)-hexanoic acid [2-(4-vinyl-benzylcarbamoyl)-ethyl]-amide

There total 3 articles about (S)-2,6-Bis-(2,2,2-trifluoro-acetylamino)-hexanoic acid [2-(4-vinyl-benzylcarbamoyl)-ethyl]-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 3-[(S)-2,6-Bis-(2,2,2-trifluoro-acetylamino)-hexanoylamino]-propionic acid

: 50325-49-0
p-vinylbenzylamine

: 849586-31-8
(S)-2,6-Bis-(2,2,2-trifluoro-acetylamino)-hexanoic acid [2-(4-vinyl-benzylcarbamoyl)-ethyl]-amide

Guidance literature:: With benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In 1-methyl-pyrrolidin-2-one; at 20 ℃; for 16h;
DOI:10.1021/ma047621n

Reference yield:

: 849586-24-9
3-[2,6-bis-(2,2,2-trifluoro-acetylamino)-hexanoylamino]-propionic acid tert-butyl ester

: 849586-31-8
(S)-2,6-Bis-(2,2,2-trifluoro-acetylamino)-hexanoic acid [2-(4-vinyl-benzylcarbamoyl)-ethyl]-amide

Guidance literature:: Multi-step reaction with 2 steps

1: 99 percent / trifluoroacetic acid / CH₂Cl₂ / 2 h / 20 °C

2: 98 percent / O-benzotriazole-N,N,N',N'-tetramethyluronium PF₆; N-hydroxybenzotriazole; N,N-diisopropylethylamine / 1-methyl-pyrrolidin-2-one / 16 h / 20 °C

With benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In 1-methyl-pyrrolidin-2-one; dichloromethane;
DOI:10.1021/ma047621n

Reference yield:

: 329-53-3
N^α,N^ε-bis(trifluoroacetyl)-L-lysine

: 849586-31-8
(S)-2,6-Bis-(2,2,2-trifluoro-acetylamino)-hexanoic acid [2-(4-vinyl-benzylcarbamoyl)-ethyl]-amide

Guidance literature:: Multi-step reaction with 3 steps

1: 98 percent / O-benzotriazole-N,N,N',N'-tetramethyluronium PF₆; N-hydroxybenzotriazole; N,N-diisopropylethylamine / dimethylformamide / 16 h / 20 °C

2: 99 percent / trifluoroacetic acid / CH₂Cl₂ / 2 h / 20 °C

3: 98 percent / O-benzotriazole-N,N,N',N'-tetramethyluronium PF₆; N-hydroxybenzotriazole; N,N-diisopropylethylamine / 1-methyl-pyrrolidin-2-one / 16 h / 20 °C

With benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In 1-methyl-pyrrolidin-2-one; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/ma047621n